Wegener’s Granulomatosis or Granulomatosis with Polyangiitis is a disorder characterized by inflammation of blood vessels in various organs of the body. Usually small and medium sized blood vessels are affected. Upper and lower respiratory tract and kidneys are the common organs affected, however, any organ may get affected with this disorder. Symptoms depend on the type of the organ involved. When respiratory tract is involved, cough, nasal discharge and shortness of breath are the common symptoms. When kidneys are involved there may be leg swellings, blood in the urine or protein in the urine. Diagnosis is usually made by obtaining a tissue sample of the organ involved. Treatment is usually given with steroids. Immunosuppressants are commonly used along with steroids.
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