Ulcerative Colitis

Ulcerative Colitis

Last Reviewed : 12/29/2020
Ulcerative Colitis

Ulcerative colitis (UC) is a chronic relapsing form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon. Symptoms can range from mild to severe with disease onset usually occurring in young adults. Its course is unpredictable but with a strong likelihood of lifelong disease. The disease is a type of colitis, which is a group of diseases that cause inflammation of the colon, the largest section of the large intestine, either in segments or completely. The primary symptom of active disease isdiarrhea mixed with blood. UC has much in common with Crohn's disease, another form of IBD, but unlike Crohn's disease, UC affects only the colon and rectum, rather than the whole GI tract. UC is an intermittent disease, with periods of exacerbated symptoms alternating with relatively symptom-free periods. Although the symptoms of UC can sometimes diminish on their own, the disease usually requires treatment to go into remission.

Although UC has no known cause, there is a presumed genetic risk. This may also involve microbiota and the immune system. Rates tend to be higher in wealthier countries, which may indicate the increased rate is due to better diagnosis. It may also indicate that an industrial or Western diet and lifestyle increases the rate of disease, including symptoms which may or may not be related to UC. The disease may be triggered in a susceptible person by environmental factors. Dietary modification may reduce the discomfort of a person with the disease.

Like Crohn's disease, UC is both classified as and managed as an autoimmune disease. Treatment is with anti-inflammatory medications, immunosuppression, and biological therapy targeting specific components of the immune response.

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.




Basic information:

http://www.healthline.com/health/ulcerative-colitis health line ulcerative colitis

https://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/ulcerative-colitis/pages/facts.aspx national institute of diabetes and digestive and kidney diseases ulcerative colitis

http://www.nhs.uk/conditions/ulcerative-colitis/pages/introduction.aspx nhs uk ulcerative colitis

http://www.mayoclinic.org/diseases-conditions/ulcerative-colitis/basics/symptoms/con-20043763 mayoclinic ulcerative colitis

http://www.webmd.com/ibd-crohns-disease/ulcerative-colitis/ulcerative-colitis-topic-overview web md ulcerative colitis - topic overview

https://medlineplus.gov/ency/article/000250.htm medline plus ulcerative colitis

http://patients.gi.org/topics/ulcerative-colitis/ american college of gastro enterology ulcerative colitis

http://www.health.com/health/gallery/0,,20500615,00.html health .com 14 foods to avoid if you have ulcerative colitis

http://my.clevelandclinic.org/health/diseases_conditions/hic_ulcerative_colitis cleveland clinic ulcerative colitis ulcerative colitis

http://www.nytimes.com/health/guides/disease/ulcerative-colitis/overview.html new york times ulcerative colitis

http://www.bupa.co.uk/health-information/directory/u/ulcerative-colitis bupa ulcerative colitis

http://www.cdd.com.au/pages/disease_info/ulcerative_colitis.html center for digestive diseases ulcerative colitis

http://www.merckmanuals.com/home/digestive-disorders/inflammatory-bowel-diseases-ibd/ulcerative-colitis merck manuals(professional version) ulcerative colitis

http://www.livescience.com/40309-ulcerative-colitis.html live science ulcerative colitis: symptoms & treatment

https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/crohns-disease-and-ulcerative-colitis better health crohn's disease and ulcerative colitis

http://umm.edu/health/medical/altmed/condition/ulcerative-colitis university of maryland medical center ulcerative colitis

https://www.southerncross.co.nz/group/medical-library/ulcerative-colitis-causes-symptoms-treatment southern cross medical library ulcerative colitis - causes, symptoms, treatment

http://www.healthnavigator.org.nz/health-a-z/u/ulcerative-colitis/ health navigator ulcerative colitis


Advanced information:

http://www.medicinenet.com/ulcerative_colitis/article.htm medicine net ulcerative colitis

http://emedicine.medscape.com/article/183084-overview medscape ulcerative colitis

http://patient.info/health/ulcerative-colitis-leaflet patient ulcerative colitis

http://www.emedicinehealth.com/ulcerative_colitis/article_em.htm emedicine health ulcerative colitis

http://radiopaedia.org/articles/ulcerative-colitis radiopedia ulcerative colitis

http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/gastroenterology/ulcerative-colitis/ cleveland clinic ulcerative colitis

http://www.medicalnewstoday.com/articles/306423.php medical news today ulcerative colitis may be treatable with vinegar

http://www.uptodate.com/contents/ulcerative-colitis-beyond-the-basics upto date ulcerative colitis overview



al roujayee a. cutaneous manifestations of inflammatory bowel disease. saudi j gastroenterol [serial online] 2007 [cited 2016 jul 29];13:159-62. available from: http://www.saudijgastro.com/text.asp?2007/13/4/159/36744

http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc4227676&blobtype=pdf carmo amd, santos fm, ortiz-agostinho cl, nishitokukado i, frota cs, et al. (2014) cytomegalovirus infection in inflammatory bowel disease is not associated with worsening of intestinal inflammatory activity. plos one 9(11): e111574. doi:10.1371/journal.pone.0111574

http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc3978022&blobtype=pdf zhao l-n, li j-y, yu t, chen g-c, yuan y-h, et al. (2014) 5-aminosalicylates reduce the risk of colorectal neoplasia in patients with ulcerative colitis: an updated meta-analysis. plos one 9(4): e94208. doi:10.1371/journal.pone.0094208

http://www.hindawi.com/journals/tswj/2013/296470/ lingna ye, qian cao, and jianfeng cheng, “review of inflammatory bowel disease in china,” the scientific world journal, vol. 2013, article id 296470, 6 pages, 2013. doi:10.1155/2013/296470

http://www.hindawi.com/journals/bmri/2015/505878/ maria jose saez-lara, carolina gomez-llorente, julio plaza-diaz, and angel gil, “the role of probiotic lactic acid bacteria and bifidobacteria in the prevention and treatment of inflammatory bowel disease and other related diseases: a systematic review of randomized human clinical trials,” biomed research international, vol. 2015, article id 505878, 15 pages, 2015. doi:10.1155/2015/505878

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0004-28032014000400271&lng=en&tlng=en arq. gastroenterol. vol.51 no.4 são paulo oct./dec. 2014 http://dx.doi.org/10.1590/s0004-28032014000400002 original articles:inflammatory bowel disease in hispanic communities: a concerted south american approach could identify the aetiology of crohn’s disease and ulcerative colitis by affifa farrukh et al.,

http://implementationscience.biomedcentral.com/articles/10.1186/1748-5908-5-48 the grade approach for assessing new technologies as applied to apheresis devices in ulcerative colitis by nora ibargoyen-roteta et al., implementation science20105:48 doi: 10.1186/1748-5908-5-48

http://www.hindawi.com/journals/jir/2013/196012/ omar i. saadah and jamil a. al-mughales, “pediatric inflammatory bowel disease with cytoplasmic staining of antineutrophil cytoplasmic antibodies,” clinical and developmental immunology, vol. 2013, article id 196012, 5 pages, 2013. doi:10.1155/2013/196012

http://journal.frontiersin.org/article/10.3389/fimmu.2012.00345/full review article front. immunol., 27 november 2012 | http://dx.doi.org/10.3389/fimmu.2012.00345 application of multistem® allogeneic cells for immunomodulatory therapy: clinical progress and pre-clinical challenges in prophylaxis for graft versus host disease by bart vaes et al.,

http://www.hindawi.com/journals/crigm/2013/679147/ giovanni casella, claudio camillo cortelezzi, delodovici marialuisa, et al., “cerebral arterial thrombosis in ulcerative colitis,” case reports in gastrointestinal medicine, vol. 2013, article id 679147, 4 pages, 2013. doi:10.1155/2013/679147

http://www.hindawi.com/journals/grp/2015/435820/ judy nee and joseph d. feuerstein, “optimizing the care and health of women with inflammatory bowel disease,” gastroenterology research and practice, vol. 2015, article id 435820, 8 pages, 2015. doi:10.1155/2015/435820

balmus im, ciobica a, trifan a, stanciu c. the implications of oxidative stress and antioxidant therapies in inflammatory bowel disease: clinical aspects and animal models. saudi j gastroenterol [serial online] 2016 [cited 2016 jul 29];22:3-17. available from: http://www.saudijgastro.com/text.asp?2016/22/1/3/173753

jani k, shah a. laparoscopic total proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. j min access surg [serial online] 2015 [cited 2016 jul 29];11:177-83. available from: http://www.journalofmas.com/text.asp?2015/11/3/177/140212

http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc4682717&blobtype=pdf : huoponen s, blom m (2015) a systematic review of the cost-effectiveness of biologics for the treatment of inflammatory bowel diseases. plosone 10(12): e0145087. doi:10.1371/journal.pone.0145087

al-mobaireek kf. ulcerative colitis and chronic granulomatous disease: a case report and review of the literature. saudi j gastroenterol [serial online] 2001 [cited 2016 jul 29];7:119-21. available from: http://www.saudijgastro.com/text.asp?2001/7/3/119/33424

http://www.nejm.org/doi/full/10.1056/nejmoa050516#t=article infliximab for induction and maintenance therapy for ulcerative colitis by paul rutgeerts, m.d., ph.d., et al., n engl j med 2005; 353:2462-2476december 8, 2005doi: 10.1056/nejmoa050516

http://www.nature.com/nrgastro/journal/v3/n7/full/ncpgasthep0528.html nature clinical practice gastroenterology & hepatology (2006) 3, 390-407 doi:10.1038/ncpgasthep0528
mechanisms of disease: pathogenesis of crohn's disease and ulcerative colitis by r balfour sartor

http://iai.asm.org/content/68/3/1542.full colonic bacteria express an ulcerative colitis panca-related protein epitope by o. cohavy et al., doi: 10.1128/iai.68.3.1542-1548.2000infect. immun. march 2000 vol. 68 no. 3 1542-1548


Related topics:

http://www.drhomeo.com/ulcerative-colitis/ulcerative-colitis-homeopathic-treatment/ dr..homeo ulcerative colitis its homeopathic treatment


Related videos:

https://www.youtube.com/watch?v=jmapmby0cfq what is ulcerative colitis?

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https://www.youtube.com/watch?v=qokyqoftwgq colonoscopy of ulcerative colitis

https://www.youtube.com/watch?v=6mxjfyrlyqk ulcerative colitis diet alternative medicine - planet ayurveda


Presentations/quiz/newspaper articles:

http://www.dailymail.co.uk/health/article-3446200/vinegar-help-treat-bowel-condition-ulcerative-colitis.html daily mail can vinegar help treat a painful bowel condition?

read more: http://www.dailymail.co.uk/health/article-3446200/vinegar-help-treat-bowel-condition-ulcerative-colitis.html#ixzz4g5ehpqam

http://www.huffingtonpost.in/entry/living-with-ulcerative-colitis_b_7818514 the huffingtons post living with ulcerative colitis

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