Transjugular intrahepatic portosystemic shunt or transjugular intrahepatic portosystemic stent shunting (commonly abbreviated as TIPS or TIPSS) is an artificial channel within the liver that establishes communication between the inflow portal veinand the outflow hepatic vein. It is used to treat portal hypertension (which is often due to liver cirrhosis) which frequently leads to intestinal bleeding, life-threatening esophageal bleeding (esophageal varices) and the buildup of fluid within the abdomen (ascites).
An interventional radiologist creates the shunt using an image-guided endovascular (via the blood vessels) approach, with thejugular vein as the usual entry site.
The procedure was first described by Josef Rösch in 1969 at Oregon Health and Science University. It was first used in a human patient by Dr. Ronald Colapinto, of the University of Toronto, in 1982, but did not become reproducibly successful until the development of endovascular stents in 1985. In 1988 the first successful TIPS was realized by M. Rössle, G.M. Richter, G. Nöldge and J. Palmaz at the University of Freiburg. The procedure has since become widely accepted as the preferred method for treating portal hypertension that is refractory to medical therapy, replacing the surgical portocaval shunt in that role.
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http://www.jemds.com/data_pdf/3-kamlesh---rks%20----gir.pdf keshava h. k, chikkalingaiah, kamalesh t. n, vinayaka g. p, shashidhar b. “usefulness of meld score in predicting in-hospital mortality in patients with end stage liver disease: an observational study”. journal of evolution of medical and dental sciences 2015; vol. 4, issue 45, june 04; page: 7734-7740, doi: 10.14260/jemds/2015/1126
http://gut.bmj.com/content/47/2/288.longgut 2000;47:288-295 doi:10.1136/gut.47.2.288 liver disease long term outcome after transjugular intrahepatic portosystemic stent-shunt in non-transplant cirrhotics with hepatorenal syndrome: a phase ii study by k a brensinget al.,
http://www.hindawi.com/journals/ijh/2011/398291/ sundeep j. punamiya and deepak n. amarapurkar, “role of tips in improving survival of patients with decompensated liver disease,” international journal of hepatology, vol. 2011, article id 398291, 5 pages, 2011. doi:10.4061/2011/398291
anuradha rao t n, rastogi h, pandey u c. pictorial essay : trans-jugular intra-hepatic porto-systemic shunt (tips). indian j radiol imaging [serial online] 2001 [cited 2016 aug 5];11:17-22. available from: http://www.ijri.org/text.asp?2001/11/1/17/28303
http://www.bloodjournal.org/content/99/11/4246?sso-checked=true transjugular intrahepatic portosystemic shunt for treatment of portal hypertension due to extramedullary hematopoiesis in idiopathic myelofibrosis by bernhard angermayr, manfred cejna, maria schoder, fritz wrba, peter valent, alfred gangl, markus peck-radosavljevic blood 2002 99:4246-4247; doi:10.1182/blood-2002-01-0282
huang l, yu qs, zhang q, liu jd, wang z. transjugular intrahepatic portosystemic shunt versus surgical shunting in the management of portal hypertension. chin med j [serial online] 2015 [cited 2016 aug 5];128:826-34. available from: http://www.cmj.org/text.asp?2015/128/6/826/152676