Thyroid cancer is a cancer originating from follicular or parafollicular thyroid cells. These cells give rise to both well-differentiatedcancers—papillary thyroid cancer (PTC) and follicular thyroid cancer (FTC)—and anaplastic thyroid cancer (ATC), whose anaplasticcells are poorly differentiated. The second cell type, the C or parafollicular cell, produces the hormone calcitonin and is the cell of origin for medullary thyroid cancer (MTC).
The most effective management of aggressive thyroid cancers is surgical removal of thyroid gland (thyroidectomy) followed byradioactive iodine ablation and TSH-suppression therapy. Chemotherapy or radiotherapy may also be used in cases of distantmetastases or advanced cancer stage. Five year survival rates are 97.8% in the United States.
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http://online.liebertpub.com/doi/pdf/10.1089/thy.2015.0020 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer THYROID Volume 26, Number 1, 2016 ª American Thyroid Association ª Mary Ann Liebert, Inc.DOI: 10.1089/thy.2015.0020
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008302.pub2/full Recombinant human thyrotropin (rhTSH) aided radioiodine treatment for residual or metastatic differentiated thyroid cancer by Chao Ma et al, First published: 10 November 2010 Assessed as up-to-date: 29 November 2009,Editorial Group: Cochrane Metabolic and Endocrine Disorders Group DOI: 10.1002/14651858.CD008302.pub2