Tetralogy of Fallot (TOF) is a congenital heart defect which is classically understood to involve four anatomical abnormalities of the heart (although only three of them are always present). It is the most commoncyanotic heart defect and the most common cause of blue baby syndrome. TOF is usually a right-to-left shunt, in which higher resistance to right ventricular outflow results in more severe cyanosis symptoms.
TOF is treated with corrective surgery, usually within the first year of life, but presents with long-term problems including arrhythmia, pulmonary regurgitation, and re-operation.
In the United States, the prevalence of TOF is 3.9 per 10,000 live births and accounts for 7-10% of congenital heart diseases. It was described in 1672 by Niels Stensen, in 1773 by Edward Sandifort, and in 1888 by the French physician Étienne-Louis Arthur Fallot, after whom it is named.
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http://asecho.org/wordpress/wp-content/uploads/2014/01/repairedtof_feb2014.pdf multimodality imaging guidelines for patients with repaired tetralogy of fallot: a report from the american society of echocardiography developed in collaboration with the society for cardiovascular magnetic resonance and the society for pediatric radiology by anne marie valente, md, fase(j am soc echocardiogr 2014;27:111-41.)
solanki sl, jain a, singh a, sharma a. low-dose sequential combined-spinal epidural anesthesia for cesarean section in patient with uncorrected tetrology of fallot. saudi j anaesth [serial online] 2011 [cited 2016 jul 24];5:320-2. available from: http://www.saudija.org/text.asp?2011/5/3/320/84111
vyas a, rajeshwari k, kurien s, mehta v, pandarikar n, tyagi s. an unusual cardiac mass resolving with antitubercular treatment. ann pediatr card [serial online] 2014 [cited 2016 jul 24];7:204-6. available from: http://www.annalspc.com/text.asp?2014/7/3/204/140849
karande s c, sheth s s, dalvi b v, lahiri k, shah m d. congenital intermittent atrio-ventricular dissociation in tetralogy of fallot (a case report). j postgrad med [serial online] 1991 [cited 2016 aug 1];37:58-61. available from: http://www.jpgmonline.com/text.asp?1991/37/1/58/798
http://content.onlinejacc.org/article.aspx?articleid=1124242 long-term survival in patients with repair of tetralogy of fallot: 36-year follow-up of 490 survivors of the first year after surgical repair by georg nollert, md et al., j am coll cardiol. 1997;30(5):1374-1383. doi:10.1016/s0735-1097(97)00318-5