Tetrology of fallot

Tetrology of fallot

Last Reviewed : 12/25/2020
Tetrology of fallot

Tetralogy of Fallot (TOF) is a congenital heart defect which is classically understood to involve four anatomical abnormalities of the heart (although only three of them are always present). It is the most commoncyanotic heart defect and the most common cause of blue baby syndrome. TOF is usually a right-to-left shunt, in which higher resistance to right ventricular outflow results in more severe cyanosis symptoms.

TOF is treated with corrective surgery, usually within the first year of life, but presents with long-term problems including arrhythmia, pulmonary regurgitation, and re-operation.

In the United States, the prevalence of TOF is 3.9 per 10,000 live births and accounts for 7-10% of congenital heart diseases. It was described in 1672 by Niels Stensen, in 1773 by Edward Sandifort, and in 1888 by the French physician Étienne-Louis Arthur Fallot, after whom it is named.


We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.




Basic information:

https://www.nhlbi.nih.gov/health/health-topics/topics/tof national heart lung and blood institute tetralogy of fallot

http://www.mayoclinic.org/diseases-conditions/tetralogy-of-fallot/basics/definition/con-20043262 mayoclinic tetralogy of fallot

http://www.heart.org/heartorg/conditions/congenitalheartdefects/aboutcongenitalheartdefects/tetralogy-of-fallot_ucm_307038_article.jsp tetralogy of fallot

https://medlineplus.gov/ency/article/001567.htm medlineplus tetralogy of fallot

http://kidshealth.org/en/parents/tetralogy-of-fallot.html kids health tetralogy of fallot

http://www.healthline.com/health/tetralogy-of-fallot health line tetralogy of fallot

http://www.webmd.com/heart-disease/tetralogy-fallot web md tetralogy of fallot

http://www.chd-uk.co.uk/types-of-chd-and-operations/tetralogy-of-fallot-tof/ congenital heart defects uk tetralogy of fallot

http://www.easyauscultation.com/cases?coursecaseorder=5&courseid=29 easy auscultation tetralogy of fallot

http://my.clevelandclinic.org/childrens-hospital/health-info/diseases-conditions/tetralogy-of-fallot-childrens-overview cleveland clinic tetralogy of fallot

http://umm.edu/health/medical/ency/articles/tetralogy-of-fallot university of maryland medical center tetralogy of fallot

http://www.nhs.uk/conditions/congenital-heart-disease/pages/treatment.aspx nhs uk congenital heart disease - treatment

http://www.nytimes.com/health/guides/disease/tetralogy-of-fallot/overview.html new york times tetralogy of fallot

http://www.aboutkidshealth.ca/en/resourcecentres/congenitalheartconditions/understandingdiagnosis/diagnosisofcongenitalheartdefects/pages/tetralogy-of-fallot.aspx about kids health tetralogy of fallot


Advanced information:

http://emedicine.medscape.com/article/2035949-overview medscape tetralogy of fallot

http://www.emedicinehealth.com/tetralogy_of_fallot/article_em.htm http://patient.info/doctor/fallots-tetralogy emedicine health fallot's tetralogy

http://radiopaedia.org/articles/tetralogy-of-fallot radiopedia tetralogy of fallot

http://lifeinthefastlane.com/cardiovascular-curveball-009/ life in the fast lane tetraology of fallot and bt shunts by chris nickson

http://rarediseases.org/rare-diseases/tetralogy-of-fallot/ national organisation for rare diseases tetralogy of fallot

http://asecho.org/wordpress/wp-content/uploads/2014/01/repairedtof_feb2014.pdf multimodality imaging guidelines for patients with repaired tetralogy of fallot: a report from the american society of echocardiography developed in collaboration with the society for cardiovascular magnetic resonance and the society for pediatric radiology by anne marie valente, md, fase(j am soc echocardiogr 2014;27:111-41.)

https://pedclerk.bsd.uchicago.edu/page/tetrology-fallot pediatric clerkship tetralogy of fallot

http://www.physio-pedia.com/tetrology_of_fallot physiopedia tetralogy of fallot

http://www.dovemed.com/diseases-conditions/tetralogy-fallot/ dove med tetralogy of fallot

http://eradiology.bidmc.harvard.edu/learninglab/cardio/lipska.pdf eradiology tetralogy of fallot



solanki sl, jain a, singh a, sharma a. low-dose sequential combined-spinal epidural anesthesia for cesarean section in patient with uncorrected tetrology of fallot. saudi j anaesth [serial online] 2011 [cited 2016 jul 24];5:320-2. available from: http://www.saudija.org/text.asp?2011/5/3/320/84111

vyas a, rajeshwari k, kurien s, mehta v, pandarikar n, tyagi s. an unusual cardiac mass resolving with antitubercular treatment. ann pediatr card [serial online] 2014 [cited 2016 jul 24];7:204-6. available from: http://www.annalspc.com/text.asp?2014/7/3/204/140849

karande s c, sheth s s, dalvi b v, lahiri k, shah m d. congenital intermittent atrio-ventricular dissociation in tetralogy of fallot (a case report). j postgrad med [serial online] 1991 [cited 2016 aug 1];37:58-61. available from: http://www.jpgmonline.com/text.asp?1991/37/1/58/798

kejariwal d, sarkar n, roy s, bhattacharya m. fallot's tetralogy presenting with variceal bleed. j postgrad med [serial online] 2001 [cited 2016 aug 5];47:194. available from: http://www.jpgmonline.com/text.asp?2001/47/3/194/195

https://ojrd.biomedcentral.com/articles/10.1186/1750-1172-4-2 tetralogy of fallot by frederique bailliard and robert h anderson orphanet journal of rare diseases20094:2 doi: 10.1186/1750-1172-4-2

karl tr. tetralogy of fallot: current surgical perspective. ann pediatr card [serial online] 2008 [cited 2016 aug 5];1:93-100. available from: http://www.annalspc.com/text.asp?2008/1/2/93/43873

http://circ.ahajournals.org/content/100/suppl_2/ii-157 repair of tetralogy of fallot in neonates and young infants by frank a. pigula, philipe n. khalil, john e. mayer, pedro j. del nido and richard a. jonas http://dx.doi.org/10.1161/01.cir.100.suppl_2.ii-15...

http://pediatrics.aappublications.org/content/134/1/e266 pediatrics july 2014, volume 134 / issue 1 treatment of tetralogy of fallot hypoxic spell with intranasal fentanyl by daniel s. tsze, yaffa m. vitberg, joel berezow, thomas j. starc, peter s. dayan

http://www.sciencedirect.com/science/article/pii/s0735109713053795 hot topics in tetralogy of fallot by juan villafañe, md et al., journal of the american college of cardiology volume 62, issue 23, 10 december 2013, pages 2155–2166 doi:10.1016/j.jacc.2013.07.100

http://content.onlinejacc.org/article.aspx?articleid=1124242 long-term survival in patients with repair of tetralogy of fallot: 36-year follow-up of 490 survivors of the first year after surgical repair by georg nollert, md et al., j am coll cardiol. 1997;30(5):1374-1383. doi:10.1016/s0735-1097(97)00318-5

http://hmg.oxfordjournals.org/content/10/2/163.long familial tetralogy of fallot caused by mutation in the jagged1 gene by zayd a. eldadah et al., hum. mol. genet. (2001) 10 (2):163-169.doi: 10.1093/hmg/10.2.163

http://www.nejm.org/doi/full/10.1056/nejm199308263290901#t=article long-term outcome in patients undergoing surgical repair of tetralogy of fallot joseph g. murphy n engl j med 1993; 329:593-599august 26, 1993doi: 10.1056/nejm199308263290901

http://www.nature.com/gim/journal/v3/n1/full/gim200112a.html genetics in medicine (2001) 3, 56–60; doi:10.1097/00125817-200101000-00012 tetralogy of fallot associated with chromosome 22q11.2 deletion in adolescents and young adults by kazuo momma et al.,

http://archpedi.jamanetwork.com/article.aspx?articleid=500926 congestive heart failure in tetralogy of fallotreport of two cases by w. t. dungan, md; a. yilmaz oztalay, md am j dis child. 1964;107(4):398-403. doi:10.1001/archpedi.1964.02080060400012.

http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002843 rare copy number variations in adults with tetralogy of fallot implicate novel risk gene pathways by candice k. silversides http://dx.doi.org/10.1371/journal.pgen.1002843


Other articles:

http://www.petmd.com/dog/conditions/cardiovascular/c_dg_tetralogy_of_fallot pet md tetralogy of fallot in dogs

http://www.vetmed.ucdavis.edu/vmth/small_animal/cardio_kittleson/cases/case29/text.htm vet md case studies in small animal

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0102-09352000000500003 arq. bras. med. vet. zootec. vol.52 n.5 belo horizonte oct. 2000 http://dx.doi.org/10.1590/s0102-09352000000500003 clinical diagnosis and alternative surgical treatment of tetralogy of fallot in a dog. a case report m.h.m.a larsson

http://www.merckvetmanual.com/mvm/circulatory_system/congenital_and_inherited_anomalies_of_the_cardiovascular_system/tetralogy_of_fallot.html merck vet manuals tetralogy of fallot


Related videos:

https://www.youtube.com/watch?v=drgusgvl_4q tetralogy of fallot

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https://www.youtube.com/watch?v=uhv2rhntpjg tetralogy of fallot

https://www.youtube.com/watch?v=79wsyalvwse tetralogy of fallot


Presentations/quiz/newspaper articles:

http://abcnews.go.com/health/heart-disease-socially-isolates-teens-struggling-normal-girl/story?id=18358705 abc news heart disease socially isolates teens struggling to be normal

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