Restless Leg Syndrome

Restless Leg Syndrome

Last Reviewed : 12/25/2020
Restless Leg Syndrome

Restless legs syndrome (RLS) is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can affect the arms, torso, head, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief.

RLS sensations range from pain or an aching in the muscles, to "an itch you can't scratch", a "buzzing sensation", an unpleasant "tickle that won't stop", a "crawling" feeling, or limbs jerking while awake. The sensations typically begin or intensify during quiet wakefulness, such as when relaxing, reading, studying, or trying to sleep. Additionally, most individuals with RLS have periodic limb movement disorder (limbs jerking during sleep), which is an objective physiologic marker of the disorder and is associated with sleep disruption. It can be caused by low iron levels.

Treatment is often with levodopa or a dopamine agonist such as pramipexole. Some controversy surrounds the marketing of drug treatments for RLS. It is a "spectrum" disease with some people experiencing only a minor annoyance and others having major disruption of sleep and impairments in quality of life. It is believed that as many as 12 million individuals in the United States have RLS, and many more are undiagnosed.

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.



Basic information: cleveland clinic restless leg syndrome web md restless legs syndrome national institute of neurological disorders and stroke restless leg syndrome health line best treatments for restless leg syndrome nhs uk restless legs syndrome - causes better health restless leg syndrome help guide restless leg syndrome mayoclinic restless leg syndrome sleep association about restless legs syndrome university of maryland restless legs syndrome and related disorders family doctor restless legs syndrome stanford health care restless legs syndrome (rls) everyday health restless legs syndrome treatment medline plus restless legs syndrome restless legs syndrome live science restless legs syndrome: symptoms and treatment


Advanced information: medscape restless legs syndrome patient restless legs syndrome medicine net restless leg syndrome veterans affairs research communications. "study ties restless legs syndrome to heart, kidney problems: research draws on database of 3 million veterans." sciencedaily. sciencedaily, 8 october 2015. newyork times restless leg syndrome in-depth report emedicine health restless legs syndrome (rls) medical news today what is restless legs syndrome? how to treat restless legs syndrome


Research: arq. neuro-psiquiatr. vol.66 no.2b são paulo june 2008 views and reviews:anticonvulsants to treat idiopathic restless legs syndrome: systematic review by cristiane fiquene conti et al.,

basu a, kundu s, khurana h. olanzapine-induced restless leg syndrome: a case report and review of literature. indian j pharmacol [serial online] 2014 [cited 2016 jul 18];46:450-2. available from:

rossi f h, liu w, geigel e, castaneda s, rossi e m, schnacky k. painful legs and moving toes syndrome responsive to pregabalin. j postgrad med [serial online] 2015 [cited 2016 jul 18];61:116-9. available from: review article front. neurol., 08 february 2013 | central pattern generator for locomotion: anatomical, physiological, and pathophysiological considerations by pierre a. guertin

natarajan r. review of periodic limb movement and restless leg syndrome. j postgrad med [serial online] 2010 [cited 2016 jul 18];56:157-62. available from:


Related topics: life force homeopathy restless leg syndrome


Other helpful resources(support groups): restless leg syndrome foundation


Related videos: understanding restless legs syndrome (health guru) what is restless leg syndrome? restless leg syndrome? sleep time lapse - restless leg syndrome? gluten sensitivity and restless leg syndrome.mp4 what is restless leg syndrome? what is restless leg syndrome?


Presentations/quiz/newspaper articles: times of india is restless legs syndrome affecting your sleep? daily mail tired all the time? restless legs syndrome could be the real reason why

read more: huffington post restless legs syndrome: causes, symptoms and treatment explained huffingtons post do i have restless legs syndrome?



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