prolactinoma
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Prolactinoma

Prolactinoma

Last Reviewed : 12/24/2020
Prolactinoma

A prolactinoma is a benign tumor (adenoma) of the pituitary gland that produces a hormone called prolactin. It is the most common type of pituitary tumor. Symptoms of prolactinoma are too much prolactin in the blood (hyperprolactinemia), or those caused by pressure of the tumor on surrounding tissues..

Prolactin stimulates the breast to produce milk, and has many other functions such as regulation of mood. Hence prolactin levels are usually higher during pregnancy and after childbirth. After delivery of a baby, a mother's prolactin levels come down to normal a few weeks after breastfeeding is discontinued. Each time the milk is dispensed, prolactin levels rise; this process may cycle to maintain milk production. In males it is responsible for the sexual refractory period after orgasm and excess levels can lead to erectile dysfunction.

Based on size, a prolactinoma can be classified as a microprolactinoma (<10 mm diameter) or macroprolactinoma (>10 mm diameter).

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.

 

 

Basic information:

http://www.mayoclinic.org/diseases-conditions/prolactinoma/basics/definition/con-20028094 mayoclinic prolactinoma

https://medlineplus.gov/ency/article/000336.htm medline plus prolactinoma

https://www.niddk.nih.gov/health-information/health-topics/endocrine/prolactinoma/pages/fact-sheet.aspx national institute for diabetes and digestive and kidney diseases prolactinoma

http://www.nytimes.com/health/guides/disease/prolactinoma/overview.html new york times prolactinoma

http://umm.edu/health/medical/ency/articles/prolactinoma university of maryland medical center prolactinoma

http://www.dovemed.com/diseases-conditions/prolactinoma/ dove med prolactinoma

 

Advanced information:

http://emedicine.medscape.com/article/124634-overview medscape prolactinoma

http://patient.info/in/health/prolactinoma patient prolactinoma

http://patient.info/in/doctor/hyperprolactinaemia-and-prolactinoma patient hyperprolactinaemia and prolactinoma

http://www.medicinenet.com/prolactinoma/article.htm medicine net.com prolactinoma (pituitary tumor)

http://www.uptodate.com/contents/high-prolactin-levels-and-prolactinomas-beyond-the-basics upto date patient information: high prolactin levels and prolactinomas (beyond the basics)

http://www.healio.com/endocrinology/neuroendocrinology/news/print/endocrine-today/%7b4e6774f1-a08e-473b-9ff3-2926d5917521%7d/middle-aged-man-diagnosed-with-giant-invasive-prolactinoma healio middle-aged man diagnosed with giant invasive prolactinoma

http://radiopaedia.org/cases/pituitary-macroadenoma-prolactinoma radiopedia pituitary macroadenoma - prolactinoma

http://www.aafp.org/afp/2013/0901/p319-s1.html prolactinoma am fam physician. 2013 sep 1;88(5):online.

https://www.symptoma.com/en/info/prolactinoma symptoma prolactinoma

 

Research:

laway ba, mir sa. pregnancy and pituitary disorders: challenges in diagnosis and management. indian j endocr metab [serial online] 2013 [cited 2016 jul 16];17:996. available from: http://www.ijem.in/text.asp?2013/17/6/996/122608

http://www.jemds.com/data_pdf/1_ashwin-.pdf jyothi jsa, ramya p, chandra as, et al. multiplanar mri and ct imaging of sellar and parasellar tumourswith clinical and pathological correlation. j.evolution med.dent. sci. 2016;5(19):969-977,doi: 10.14260/jemds/2016/225

furtado sv, venkatesh pk, ghosal n, hegde as. coexisting intracranial tumors with pituitary adenomas: genetic association or coincidence?. j can res ther [serial online] 2010 [cited 2016 jul 16];6:221-3. available from: http://www.cancerjournal.net/text.asp?2010/6/2/221/65246

http://jdmdonline.biomedcentral.com/articles/10.1186/2251-6581-12-3 giant prolactinoma: case report and review of literature by masoud rahmanian et al., journal of diabetes & metabolic disorders201312:3 doi: 10.1186/2251-6581-12-3

http://journal.frontiersin.org/article/10.3389/fendo.2015.00085/full mini review article front. endocrinol., 26 may 2015 | http://dx.doi.org/10.3389/fendo.2015.00085 managing prolactinomas during pregnancy by mussa hussain almalki

http://www.hindawi.com/journals/crinm/2016/8371697/ constantine l. karras, isaac josh abecassis, zachary a. abecassis, et al., “clival ectopic pituitary adenoma mimicking a chordoma: case report and review of the literature,” case reports in neurological medicine, vol. 2016, article id 8371697, 8 pages, 2016. doi:10.1155/2016/8371697

bhat mh, mushtaq s, saba s, saif r, ali g. cabergoline-induced tricuspid regurgitation: case report and review of literature. indian j endocr metab [serial online] 2011 [cited 2016 jul 16];15:137-9. available from: http://www.ijem.in/text.asp?2011/15/2/137/81949

http://journal.frontiersin.org/article/10.3389/fendo.2016.00054/full review article front. endocrinol., 31 may 2016 | http://dx.doi.org/10.3389/fendo.2016.00054 human pituitary adenoma proteomics: new progresses and perspectives by xianquan zhan et al.,

http://www.sciencedirect.com/science/article/pii/s2214751915000183 case reports & case series (crp)a case of giant prolactinoma, initially misdiagnosed as sinonasal neuroendocrine carcinoma by yasaman mohtasebi, m.d et al., interdisciplinary neurosurgery volume 2, issue 3, september 2015, pages 126–128 doi:10.1016/j.inat.2015.05.001

http://www.hindawi.com/journals/crim/2010/573252/ elvis henrique santos andrade, pedro mario pan, paula f. ramalho da silva, and ary gadelha, “new insights in the management of antipsychotics in the treatment of schizophrenia in a patient with prolactinoma: a case report and review of the literature,” case reports in medicine, vol. 2010, article id 573252, 3 pages, 2010. doi:10.1155/2010/573252

chaurasia pk, singh d, meher s, saran r k, singh h. epistaxis as first clinical presentation in a child with giant prolactinoma: case report and review of literature. j pediatr neurosci [serial online] 2011 [cited 2016 jul 16];6:134-7. available from: http://www.pediatricneurosciences.com/text.asp?2011/6/2/134/92840

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0004-27302014000200118 arq bras endocrinol metab vol.58 no.2 são paulo mar. 2014 http://dx.doi.org/10.1590/0004-2730000002961 prolactinoma by andrea glezer

https://www.karger.com/article/fulltext/236081 prolactinoma in children and adolescents by fideleff h.l. boquete h.r. suárez m.g. azaretzky m. horm res 2009;72:197–205
(doi:10.1159/000236081)

http://www.inat-journal.com/article/s2214-7519(15)00018-3/fulltext a case of giant prolactinoma, initially misdiagnosed as sinonasal neuroendocrine carcinoma by mohtasebi, yasaman et al.interdisciplinary neurosurgery: advanced techniques and case management , volume 2 , issue 3 , 126 - 128

 

Related topics:

http://www.ayurvedacollege.com/articles/students/prolactinomaandayurveda an ayurvedic interpretation and approach to the treatment of prolactin-secreting adenoma of the pituitary gland

 

Other helpful resources(support groups):

http://www.pituitary.org.uk/information/pituitary-conditions/prolactinoma/ the pitutary foundation

https://www.dailystrength.org/group/prolactinoma prolactinoma support group

 

Related videos:

https://www.youtube.com/watch?v=m7gmcgxolxs prolactinoma - my story

https://www.youtube.com/watch?v=civlmvyoqru prolactinoma ¦ treatment and symptoms

https://www.youtube.com/watch?v=icprsmrqtyg endonasal endoscopic prolactinoma surgery - updated version available

https://www.youtube.com/watch?v=eylhwpkgque what are prolactinomas?

https://www.youtube.com/watch?v=oefz1nsi7oe pituitary adenoma - prolactinoma - ttc

https://www.youtube.com/watch?v=rslyk-t0ni0 prolactinoma update!

 

Presentations/quiz/newspaper articles:

http://www.huffingtonpost.co.uk/2015/09/02/sue-perkins-brain-tumour-prolactinoma_n_8075504.html huffingtons post sue perkins’ brain tumour: here’s all you need to know about prolactinoma

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