Polyarteritis Nodosa(PAN)

Polyarteritis Nodosa(PAN)

Last Reviewed : 12/24/2020
Polyarteritis Nodosa(PAN)

Polyarteritis nodosa, also known as panarteritis nodosa, periarteritis nodosa, Kussmaul disease, Kussmaul-Maierdisease or PAN, is a systemic vasculitis of small- or medium-sized muscular arteries, typically involving renal and visceral vessels but sparing the pulmonary circulation. Polyarteritis nodosa may present in infants. In polyarteritis nodosa, small aneurysms are strung like the beads of a rosary, therefore making "rosary sign" an important diagnostic feature of the vasculitis.

With treatment, five-year survival is 80%; without treatment, five-year survival is 13%. Death is often a consequence of kidney failure, myocardial infarction, or stroke.

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.




Basic information:

https://medlineplus.gov/ency/article/001438.htm medline plus polyarteritis nodosa

http://www.healthline.com/health/polyarteritis-nodosa healthline polyarteritis nodosa

http://my.clevelandclinic.org/health/diseases_conditions/hic_polyarteritis_nodosa cleveland clinic polyarteritis nodosa

http://www.medicinenet.com/polyarteritis_nodosa/article.htm medicine net.com polyarteritis nodosa

http://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/vasculitis/polyarteritis-nodosa-pan merck manuals(professional version) polyarteritis nodosa

http://www.aao.org/bcscsnippetdetail.aspx?id=1a80cc5b-2d64-441e-b4c1-61a4056de26b american academy of ophthalmology polyarteritis nodosa and microscopic polyangiitis

http://www.webmd.com/arthritis/polyarteritis-nodosa web md polyarteritis nodosa

http://www.nytimes.com/health/guides/disease/polyarteritis-nodosa/overview.html new york times polyarteritis nodosa


Advanced information:

http://emedicine.medscape.com/article/330717-overview medscape polyarteritis nodosa

http://patient.info/in/doctor/polyarteritis-nodosa-pro patient polyarteritis nodosa

http://www.uptodate.com/contents/treatment-and-prognosis-of-polyarteritis-nodosa uptodate treatment and prognosis of polyarteritis nodosa

http://www.dermnetnz.org/topics/cutaneous-polyarteritis-nodosa/ dermnet nz cutaneous polyarteritis nodosa

http://rarediseases.org/rare-diseases/polyarteritis-nodosa/ national organisation of rare diseases polyarteritis nodosa

https://radiopaedia.org/articles/polyarteritis-nodosa-1 radiopedia polyarteritis nodosa

http://www.fpnotebook.com/rheum/cv/plyrtrtsnds.htm family practice notebook polyarteritis nodosa

http://www.rightdiagnosis.com/p/polyarteritis_nodosa/intro.htm right diagnosis polyarteritis nodosa

http://www.physio-pedia.com/polyarteritis_nodosa physio pedia polyarteritis nodosa

http://learningradiology.com/notes/chestnotes/polyarteritisnodosapage.htm learning radiology polyarteritis nodosa

http://www.pathologyoutlines.com/topic/kidneypan.html pathology outlines polyarteritis nodosa



subbanna pa, singh nv, swaminathan rp. cutaneous polyarteritis nodosa: a rare isolated cutaneous vasculitis. indian dermatol online j [serial online] 2012 [cited 2016 sep 25];3:21-4. available from: http://www.idoj.in/text.asp?2012/3/1/21/93488

http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc4378846&blobtype=pdf : hampson lv, whitehead j, eleftheriou d, tudur-smith c, jones r, jayne d, et al. (2015) elicitation of expert prior opinion: application to the mypan trial in childhood polyarteritis nodosa. plos one 10(3): e0120981. doi:10.1371/journal.pone.0120981

https://www.hindawi.com/journals/criu/2016/7592563/ emrah simsek, hasan yilmaz, kerem teke, ali kemal uslubas, and mustafa yuksekkaya, “spontaneous retroperitoneal haematoma due to polyarteritis nodosa: report of a case and literature review,” case reports in urology, vol. 2016, article id 7592563, 3 pages, 2016. doi:10.1155/2016/7592563

https://www.hindawi.com/journals/crim/2016/5134546/ yunus ugan, atalay dogru, hüseyin sencan, mehmet sahin, and sevket ercan tunç, “sacroiliitis and polyarteritis nodosa in a patient with familial mediterranean fever,” case reports in medicine, vol. 2016, article id 5134546, 3 pages, 2016. doi:10.1155/2016/5134546

roy ak, nandi m, ghosh sk, maiti a. classic polyarteritis nodosa in childhood. indian j dermatol [serial online] 2007 [cited 2016 sep 25];52:153-4. available from: http://www.e-ijd.org/text.asp?2007/52/3/153/35096

https://www.hindawi.com/journals/crim/2009/738293/ emmanuel ribeiro, thomas cressend, pierre duffau, et al., “rituximab efficacy during a refractory polyarteritis nodosa flare,” case reports in medicine, vol. 2009, article id 738293, 3 pages, 2009. doi:10.1155/2009/738293

https://www.hindawi.com/journals/crim/2013/741047/ amira hamzaoui, noureddine litaiem, m. smiti khanfir, sofiene ayadi, haifa nfoussi, and m. h. houman, “ischemic colitis revealing polyarteritis nodosa,” case reports in medicine, vol. 2013, article id 741047, 4 pages, 2013. doi:10.1155/2013/741047

https://www.hindawi.com/journals/arthritis/2010/687547/ nina-karen bansal and kristin michelle houghton, “cutaneous polyarteritis nodosa in childhood: a case report and review of the literature,” arthritis, vol. 2010, article id 687547, 7 pages, 2010. doi:10.1155/2010/687547

https://www.hindawi.com/journals/crirh/2014/604874/ maiko kouchi, shinji sato, masahiro kamono, et al., “a case of polyarteritis nodosa associated with cytomegalovirus infection,” case reports in rheumatology, vol. 2014, article id 604874, 3 pages, 2014. doi:10.1155/2014/604874

https://www.hindawi.com/journals/criu/2011/465353/ nicholas j. toepfer, nektarios i. lountzis, joseph c. ugoeke, and tammie c. ferringer, “polyarteritis nodosa with bilateral asynchronous testicular necrosis: a case report,” case reports in urology, vol. 2011, article id 465353, 4 pages, 2011. doi:10.1155/2011/465353

garg k, dawson l. single organ variant of polyarteritis nodosa in epididymis. j can res ther [serial online] 2015 [cited 2016 sep 25];11:662. available from: http://www.cancerjournal.net/text.asp?2015/11/3/662/138133

http://www.nejm.org/doi/full/10.1056/nejmoa1307362#t=article mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy by paulina navon elkan, m.d et al., n engl j med 2014; 370:921-931march 6, 2014doi: 10.1056/nejmoa1307362

http://www.scielo.br/scielo.php?pid=s0365-05962006000900014&script=sci_arttext&tlng=en an. bras. dermatol. vol.81 suppl.3 rio de janeiro sept./oct. 2006 http://dx.doi.org/10.1590/s0365-05962006000900014 case report cutaneous polyarteritis nodosa ? case report by izelda maria carvalho costa et al.,

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0365-05962015000700188 an. bras. dermatol. vol.90 no.3 supl.1 rio de janeiro may/june 2015 http://dx.doi.org/10.1590/abd1806-4841.20153856 case report cutaneous polyarteritis nodosa by maría alejandra matteoda et al.,

https://ped-rheum.biomedcentral.com/articles/10.1186/1546-0096-10-1 giant coronary artery aneurysms in juvenile polyarteritis nodosa: a case report by therese l canares et al., pediatric rheumatology201210:1 doi: 10.1186/1546-0096-10-1

http://journal.frontiersin.org/article/10.3389/fphar.2014.00122/full opinion article front. pharmacol., 03 june 2014 | http://dx.doi.org/10.3389/fphar.2014.00122 etanercept induces remission of polyarteritis nodosa: a case report by maurizio capuozzo et al.,

http://www.ajnr.org/content/20/1/167.full polyarteritis nodosa presenting as temporal arteritis in a 9-year-old child by robert j. bertet al., ajnr 1999 20: 167-171

http://caribbean.scielo.org/scielo.php?pid=s0043-31442006000100013&script=sci_arttext west indian med. j. vol.55 no.1 mona jan. 2006 http://dx.doi.org/10.1590/s0043-31442006000100013 case report an unusual presentation of polyarteritis nodosa: a case report by e bulbuloglu et al.,


Other helpful resources(support groups):

http://www.vasculitisfoundation.org/education/forms/polyarteritis-nodosa/ vasculitis foundation


Related videos:

https://www.youtube.com/watch?v=4bilimprye0 polyarteritis nodosa

https://www.youtube.com/watch?v=vgluwsqohii polyarteritis nodosa

https://www.youtube.com/watch?v=lvttdymrnsy polyarteritis nodosa

https://www.youtube.com/watch?v=x6cj4w-t6v4 polyarteritis nodosa

https://www.youtube.com/watch?v=tw_ipfahln0 ozen's criteria for polyarteritis nodosa (pan)


Presentations/quiz/newspaper articles:

http://www.slideshare.net/ucrheumatologyfellowship/polyarteritis-nodosa Polyarteritis Nodosa

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