Pertussis/Whooping cough/100 day cough

Pertussis/Whooping cough/100 day cough

Last Reviewed : 12/24/2020
Pertussis/Whooping cough/100 day cough

Pertussis (also known as whooping cough or 100-day cough) is a highly contagious bacterial disease. Initially, symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough. This is then followed by weeks of severe coughing fits. Following a fit of coughing, a high-pitched whoop sound or gasp may occur as the person breathes in. The coughing may last for 10 or more weeks, hence the phrase "100-day cough".A person may cough so hard that they vomit,break ribs, or become very tired from the effort. Children less than one year old may have little or no cough and instead haveperiods where they do not breathe. The time between infection and the onset of symptoms is usually seven to ten days. Disease may occur in those who have been vaccinated, but symptoms are typically milder.

Pertussis is caused by the bacterium Bordetella pertussis. It is an airborne disease which spreads easily through the coughs and sneezes of an infected person. People are infectious to others from the start of symptoms until about three weeks into the coughing fits. Those treated with antibiotics are no longer infectious after five days. Diagnosis is by collecting a sample from the back of the nose and throat. This sample can then be tested by either culture or by polymerase chain reaction.

Prevention is mainly by vaccination with the pertussis vaccine. Initial immunization is recommended between six and eight weeks of age, with four doses to be given in the first two years of life. The vaccine becomes less effective over time, with additional doses often recommended for older children and adults. Antibiotics may be used to prevent the disease in those who have been exposed and are at risk of severe disease. In those with the disease, antibiotics are useful if started within three weeks of the initial symptoms, but otherwise have little effect in most people. In children less than one year old and among those who are pregnant, they are recommended within six weeks of symptom onset. Antibiotics used include erythromycin,azithromycin, clarithromycin, or trimethoprim/sulfamethoxazole. Evidence to support the effectiveness of medications for the cough is poor. Many children less than a year of age require hospitalization.

An estimated 16 million people worldwide are infected per year. Most cases occur in the developing world, and people of all ages may be affected. In 2013, it resulted in 61,000 deaths – down from 138,000 deaths in 1990. Nearly 0.5% of infected children less than one year of age die. Outbreaks of the disease were first described in the 16th century. The bacterium that causes the infection was discovered in 1906. The pertussis vaccine became available in the 1940s

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.


Basic information: medline plus pertussis natinal foundation for infectious diseases pertussis mayo clinic whooping cough victoria health.vic whooping cough web md whooping cough (pertussis) - topic overview health link bc whooping cough merck manuals(professional version) whooping cough immunize bc whooping cough healthy children whooping cough better health whooping cough nhs uk whooping cough live science old vaccine, new tricks: revive early pertussis shot, study says,pertussisinchildren/ john hopkins medical library pertussis in children


Advanced information: immunize pertussis (whooping cough): questions and answers information about the disease and vaccines pertussis (whooping cough) vaccine medscape whooping cough kids health whooping cough lab tests online pertussis tests guidelines for the public health management of pertussis in england produced by the pertussis guidelines group todars online text book of bacteriology bordetella pertussis and whooping cough medicine net whooping cough (pertussis) heaslth service executive pertussis patient whooping cough genome pertussis - mus musculus (mouse) healio unknown toxin may be cause of pertussis cough


Research: immunization coverage in who regions: a review article by rahim vakili et al., int j pediatr (supplement.1), vol.3, n.2-1, serial no.15, march 2015 update on pertussis and pertussis immunization by jung yun hong, m.d., ph.d. et al., doi: 10.3345/kjp.2010.53.5.629 korean j pediatr 2010;54(5):629-633 cad. saúde pública vol.29 no.7 rio de janeiro july 2013 review revisão should acellular pertussis vaccine be recommended to healthcare professionals? by josé cassio de moraes et al., giovanni gabutti, cecilia trucchi, michele conversano, giambattista zivelonghi, and giorgio zoppi, “booster vaccination: the role of reduced antigen content vaccines as a preschool booster,” biomed research international, vol. 2014, article id 541319, 10 pages, 2014. doi:10.1155/2014/541319 review article front. public health, 26 november 2015 | vaccines through centuries: major cornerstones of global health by inaya hajj hussein et al., pertussis vaccination in child care workers: room for improvement in coverage, policy and practice by kirsty hope et al., bmc pediatrics201212:98 doi: 10.1186/1471-2431-12-98 rev. inst. med. trop. s. paulo vol.51 no.3 são paulo may/june 2009 vaccines acellular and "low" pertussis vaccines: adverse events and the role of mutations by hisako g. higashi et al., visser o, hautvast jla, van der velden k,hulscher mejl (2016) intention to accept pertussis vaccination for cocooning: a qualitative study of the determinants. plos one 11(6): e0155861.doi:10.1371/journal.pone.0155861 mini review article front. plant sci., 27 june 2012 | madp-rts: versatile virulence factors from bacterial pathogens of plants and mammals by lennart wirthmueller* and mark j. banfield braz j med biol res, january 2004, volume 37(1) 151-158 reimmunization after bone marrow transplantation - current recommendations and perspectives by c.m. machado asymptomatic transmission and the resurgence of bordetella pertussis by benjamin m. althouse et al bmc medicine201513:146 doi: 10.1186/s12916-015-0382-8


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Presentations/quiz/newspaper articles: mercola pertussis microbe outsmarts the vaccines as experts argue about why new york times why pertussis is making a comeback

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