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Patent ductus arteriosus

Patent ductus arteriosus

Last Reviewed : 12/24/2020
Patent ductus arteriosus

 

Patent ductus arteriosus (PDA) is a condition wherein the ductus arteriosus fails to close after birth.

Early symptoms are uncommon, but in the first year of life include increased 'work of breathing' and poor weight gain. An uncorrected PDA may lead to congestive heart failure with increasing age.

The ductus arteriosus is a fetal blood vessel that closes soon after birth. In a PDA, the vessel does not close and remains "patent" (open), resulting in irregular transmission of blood between the aorta and the pulmonary artery. PDA is common in newborns with persistent respiratory problems such as hypoxia, and has a high occurrence in premature newborns. Premature newborns are more likely to be hypoxic and have PDA due to underdevelopment of the heart and lungs.

A PDA allows a portion of the oxygenated blood from the left heart to flow back to the lungs by flowing from the aorta (which has higher pressure) to the pulmonary artery. If this shunt is substantial, the neonate becomes short of breath: the additional fluid returning to the lungs increases lung pressure, which in turn increases the energy required to inflate the lungs. This uses more calories than normal and often interferes with feeding in infancy. This condition, as a constellation of findings, is called congestive heart failure.

In some congenital heart defects (such as in transposition of the great vessels) a PDA may need to remain open, as it is the only way that oxygenated blood can mix with deoxygenated blood. In these cases, prostaglandins are used to keep the DA open until surgical correction of the heart defect is completed.

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.

 

 

Basic information:

https://medlineplus.gov/ency/article/001560.htm medline plus patent ductus arteriosus

https://www.nhlbi.nih.gov/health/health-topics/topics/pda national heart lung and blood institute what is patent ductus arteriosus?

http://www.mayoclinic.org/diseases-conditions/patent-ductus-arteriosus/basics/definition/con-20028530 mayo clinic patent ductus arteriosus

http://www.aboutkidshealth.ca/en/healthaz/testsandtreatments/procedures/pages/patent-ductus-arteriosus-pda-closure-in-the-heart-catheterization-lab.aspx about kids health patent ductus arteriosus (pda): closure in the heart catheterization lab

http://kidshealth.org/en/parents/patent-ductus-arteriosus.html kids health patent ductus arteriosus

http://www.healthline.com/health/patent-ductus-arteriosus health line patent ductus arteriosus

https://www.merckmanuals.com/professional/pediatrics/congenital-cardiovascular-anomalies/patent-ductus-arteriosus-pda merck manuals(professional version) patent ductus arteriosus

http://my.clevelandclinic.org/services/heart/disorders/congenital-heart/patent-ductus-arteriousis-adults cleveland clinic patent ductus arteriosus

http://umm.edu/health/medical/ency/articles/patent-ductus-arteriosus university of maryland medical center patent ductus arteriosus

http://www.nytimes.com/health/guides/disease/patent-ductus-arteriosus/overview.html new york times patent ductus arteriosus

 

Advanced information:

http://emedicine.medscape.com/article/891096-overview medscape patent ductus arteriosus

http://patient.info/doctor/patent-ductus-arteriosus patient patent ductus arteriosus

http://radiopaedia.org/articles/patent-ductus-arteriosus radiopedia patent ductus arteriosus

http://newbornwhocc.org/pdf/pda_1503.08.pdf aiims- nicu protocols 2007

patent ductus arteriosus in preterm neonates by ramesh agarwal, ashok k deorari, vinod k paul

https://www.addl.purdue.edu/newsletters/2004/winter/arteriosis.asp patent ductus arteriosus

http://www.adhb.govt.nz/newborn/guidelines/cardiac/pda.htm newborn services clinical guideline

 

Research:

http://err.ersjournals.com/content/18/113/174.full unusual presentation for a patent ductus arteriosus by c.d. vizza, r. badagliacca, r. poscia, c. gambardella, b. pezzuto, e. crescenzi, s. papa, f. fedele european respiratory review sep 2009, 18 (113) 174-176; doi: 10.1183/09059180.00003509

http://err.ersjournals.com/content/22/130/558.full.pdf+html eisenmenger syndrome in an adult patient with a large patent ductus arteriosus by konstantinos dimopoulos european respiratory review dec 2013, 22 (130) 558-564; doi: 10.1183/09059180.00007013

http://www.kjp.or.kr/upload/2011540501-20110729165129.pdf congenital heart disease in the newborn requiring early intervention by sin weon yun, m.d. doi: 10.3345/kjp.2011.54.5.183 korean j pediatr 2011;54(5):183-191

http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc4574167&blobtype=pdf park hw, choi y-s, kim ks, kim s-n (2015) chorioamnionitis and patent ductus arteriosus: a systematic review and meta-analysis.plos one 10(9): e0138114. doi:10.1371/journal.pone.0138114

http://cardiovascularultrasound.biomedcentral.com/articles/10.1186/1476-7120-1-2 patent ductus arteriosus endarteritis in a 40-year old woman, diagnosed with transesophageal echocardiography. a case report and a brief review of the literature by nikos t kouris et al., cardiovascular ultrasound20031:2 doi: 10.1186/1476-7120-1-2

http://bmcpediatr.biomedcentral.com/articles/10.1186/1471-2431-6-15 outcome following patent ductus arteriosus ligation in premature infants: a retrospective cohort analysis by lleona cl lee bmc pediatricsbmc series ¿ open, inclusive and trusted20066:15 doi: 10.1186/1471-2431-6-15

tefera e, qureshi sa, bermudez-canete r, rubio l. percutaneous closure of patent arterial ducts in patients from high altitude: a sub-saharan experience. ann pediatr card [serial online] 2015 [cited 2016 jul 1];8:196-201. available from: http://www.annalspc.com/text.asp?2015/8/3/196/164690

https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-7-129 ligation of patent ductus arteriosus in low birth weight premature infants: timing for intervention and effectiveness of bed-side surgery by kivanç metin et al., journal of cardiothoracic surgery20127:129 doi: 10.1186/1749-8090-7-129

http://journal.publications.chestnet.org/article.aspx?articleid=2237739 treatment options for pediatric patent ductus arteriosus:systematic review and meta-analysis by jennifer y. lam et al.,

http://www.nature.com/jp/journal/v26/n1s/full/7211465a.html journal of perinatology (2006) 26, s14–s18. doi:10.1038/sj.jp.7211465 patent ductus arteriosus: pathophysiology and management by e r hermes-desantis et al.,

http://www.nejm.org/doi/full/10.1056/nejm200009073431001#t=article a comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus by bart van overmeire, m.d., ph.d n engl j med 2000; 343:674-681september 7, 2000doi: 10.1056/nejm200009073431001

http://www.scielo.br/scielo.php?pid=s2179-83972014000400364&script=sci_arttext&tlng=en rev. bras. cardiol. invasiva vol.22 no.4 são paulo oct./dec. 2014 http://dx.doi.org/10.1590/0104-1843000000061 artigos originais percutaneous occlusion of patent ductus arteriosus by juliano rathke et al.,

http://www.omicsonline.org/transcatheter-closure-of-patent-ductus-arteriosus-2161-0665.s5-005.php?aid=7915 yarrabolu tr, syamasundar rao p (2012) transcatheter closure of patent ductus arteriosus. pediat therapeut s5:005. doi: 10.4172/2161-0665.s5-005

 

Other articles:

http://www.petmd.com/dog/conditions/cardiovascular/c_multi_patent_ductus_arteriosus pet md patent ductus arteriosus

http://vet.cornell.edu/hospital/services/companion/cardiology/conditions/pda.cfm corell university college of veterinary medicine patent ductus arteriosus

http://www.merckvetmanual.com/mvm/circulatory_system/congenital_and_inherited_anomalies_of_the_cardiovascular_system/patent_ductus_arteriosus.html merck vet manual patent ductus arteriosus

http://www.peteducation.com/article.cfm?c=2+2096&aid=865 pet education.com patent ductus arteriosus (pda): a congenital heart defect in puppies

http://vetspecialists.com/patent-ductus-arteriosus-in-the-dog-pda-congenital-heart-disease/ vet specialists.com patent ductus arteriosus

http://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=3565&context=iowastate_veterinarian patent ductus arteriosus in dogs

 

Related videos:

https://www.youtube.com/watch?v=u2fgkvbir24 patent ductus arteriosus

https://www.youtube.com/watch?v=lhoxtase8cy patent ductus arteriosus

https://www.youtube.com/watch?v=7dkacqubusg patent ductus arteriosus (pda)

https://www.youtube.com/watch?v=ykbn_jmjvlk patent ductus arteriosus

https://www.youtube.com/watch?v=g_zqeqblv_g patent ductus arteriosus

https://www.youtube.com/watch?v=c43n0hakkje patent ductus arteriosus

https://www.youtube.com/watch?v=ih0ywrnrszi patent ductus arteriosus (pda) closure via left thoracotomy

 

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