Neurosyphilis is an infection of the brain or spinal cord caused by the spirochete Treponema pallidum. It usually occurs in people who have had chronic, untreated syphilis, usually about 10 to 20 years after first infectionand develops in about 25%–40% of persons who are not treated. The United States' Centers for Disease Control and Prevention (CDC) advises that neurosyphilis can occur at any stage of a syphilis infection.
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http://www.aafp.org/afp/2003/0715/p283.html diagnosis and management of syphilis by david l. brown, maj, mc, usa, and jennifer e. frank, cpt, mc, usa dewitt army community hospital, fort belvoir, virginia am fam physician. 2003 jul 15;68(2):283-290.
http://www.hindawi.com/journals/criopm/2012/621872/ sarah e. parker and john h. pula, “neurosyphilis presenting as asymptomatic optic perineuritis,” case reports in ophthalmological medicine, vol. 2012, article id 621872, 4 pages, 2012. doi:10.1155/2012/621872