Lead poisoning is a type of metal poisoning caused by increased levels of the heavy metal lead in the body. Like most toxic heavy metals, lead interferes with a variety of body processes and is toxic to many organs and tissues, including the heart, bones, intestines, kidneys, and reproductive and nervous systems. The brain is the organ most sensitive to lead exposure. Lead interferes with the development of the nervous system and is therefore particularly toxic to children, causing potentially permanent learning and behavior disorders including violence. Symptoms include abdominal pain, confusion, headache, anemia, irritability, and in severe cases seizures, coma, and death.
Routes of exposure to lead include contaminated air, water, soil, food, and consumer products. Occupational exposure is a common cause of lead poisoning in adults. According to estimates made by the National Institute of Occupational Safety and Health (NIOSH), more than 3 million workers in the United States are potentially exposed to lead in the workplace. One of the largest threats to children is lead paint that exists in many homes, especially older ones; thus children in older housing with chipping paint or lead dust from moveable window frames with lead paint are at greater risk. Prevention of lead exposure can range from individual efforts (e.g., removing lead-containing items such as piping or blinds from the home) to nationwide policies (e.g., laws that ban lead in products, reduce allowable levels in water or soil, or provide for cleanup and mitigation of contaminated soil, etc.)
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http://www.nature.com/articles/srep23716 prevention of gastrointestinal lead poisoning using recombinant lactococcus lactis expressing human metallothionein-i fusion protein by xue xiao et al, scientific reports 6, article number: 23716 (2016)doi:10.1038/srep23716