Idiopathic thrombocytopenic purpura (ITP) is defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia. ITP is an autoimmune disease with antibodies detectable against several platelet surface antigens. It causes a characteristic purpuric rash and an increased tendency to bleed, easy bruising, or extravasation of blood from capillaries into skin and mucous membranes (petechiae). Two distinct clinical syndromes manifest as an acute condition in children and a chronic condition in adults, Although most cases of acute ITP, particularly in children, are mild and self-limited, intracranial hemorrhage may occur when the platelet count drops below 10 × 109/L (< 10 × 103/µL); this occurs in 0.5-1% of children, and half of these cases are fatal.
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http://www.haematologica.org/content/93/1/98. Haematologica january 2008 93: 98-103; doi:10.3324/haematol.11582, heterogeneity of terminology and clinical definitions in adult idiopathic thrombocytopenic purpura: a critical appraisal from a systematic review of the literature