Iron overload, also known as hemochromatosis or haemochromatosis, indicates accumulation of iron in the body from any cause. The most important causes are hereditary haemochromatosis (HHC), a genetic disorder, and transfusional iron overload, which can result from repeated blood transfusions.
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http://www.aafp.org/afp/2013/0201/p183.html hereditary hemochromatosis brian k. Crownover, md, and carlton j. Covey, md, nellis family medicine residency, nellis air force base, nevada am fam physician. 2013 feb 1;87(3):183-190.
https://www.hindawi.com/journals/ah/2009/251701/ gérald le gac, chandran ka, isabelle gourlaouen, et al., “hfe-related hemochromatosis: the haptoglobin 2-2 type has a significant but limited influence on phenotypic expression of the predominant p.c282y homozygous genotype,” advances in hematology, vol. 2009, article id 251701, 6 pages, 2009. Doi:10.1155/2009/251701
Geetha r l, vani b r, murthy v s, kumar d, geethamala k. Hereditary hemochromatosis in an indian origin: a rare case report. Int j health allied sci [serial online] 2015 [cited 2016 sep 30];4:174-7. Available from: http://www.ijhas.in/text.asp?2015/4/3/174/160894
http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc4425487&blobtype=pdf : dionisio tavares niewiadonski v, dos santos bianchi jv, de almeida-neto c, gaburo n, jr,sabino ec (2015) evaluation of a high throughput method for the detection of mutations associated with thrombosis and hereditary hemochromatosis in brazilian blood donors. Plos one 10(5): e0125460. Doi:10.1371/journal.pone.0125460
http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc3887013&blobtype=pdf pretorius e, bester j, vermeulen n, lipinski b, gericke gs, et al. (2014) profound morphological changes in the erythrocytes and fibrin networks of patients with hemochromatosis or with hyperferritinemia, and their normalization by iron chelators and other agents. Plos one 9(1): e85271. Doi:10.1371/journal.pone.0085271
http://clinchem.aaccjnls.org/content/52/6/950 hereditary hemochromatosis: genetic complexity and new diagnostic approaches by dorine w. Swinkels, mirian c.h. Janssen, jürgen bergmans, joannes j.m. Marx doi: 10.1373/clinchem.2006.068684 published may 2006