Heart transplantation

A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure or severe coronary artery disease when other medical or surgical treatments have failed. As of 2016, the most common procedure is to take a functioning heart from a recently deceased organ donor (cadaveric allograft) and implant it into the patient. The patient's own heart is either removed and replaced with the donor heart (orthotopic procedure) or, less commonly, left in place to support the donor heart (heterotopic procedure). Approximately 3500 heart transplants are performed every year in the world, more than half of which occur in the US. Post-operation survival periods average 15 years. Heart transplantation is not considered to be a cure for heart disease, but a life-saving treatment intended to improve the quality of life for recipients.

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.

Basic information:

https://medlineplus.gov/ency/article/003003.htm medline plus heart transplant

http://www.hopkinsmedicine.org/healthlibrary/test_procedures/cardiovascular/heart_transplantation_procedure_92,p07974/john hopkins medical center heart transplant

http://www.heart.org/heartorg/conditions/congenitalheartdefects/caretreatmentforcongenitalheartdefects/heart-transplant_ucm_307731_article.jsp#.v6hsg9kufp0 heart.org heart transplant

https://www.nhlbi.nih.gov/health/health-topics/topics/ht national heart lung and blood institute heart transplantation

https://www.ucsfhealth.org/conditions/heart_transplant/ ucsf medical center heart transplant

http://www.healthline.com/health/heart-disease/transplants health line heart transplant surgery

http://www.webmd.com/heart-disease/heart-transplant-15646 web md heart transplant

http://my.clevelandclinic.org/services/heart/services/heart-failure-surgery/transplant cleveland clinic heart transplant

http://www.merckmanuals.com/professional/immunology-allergic-disorders/transplantation/heart-transplantation merck manuals(consumer version) heart transplantation

Advanced information:

http://emedicine.medscape.com/article/429816-overview medscape heart transplantation

http://www.medicinenet.com/heart_transplant/article.htm medicine net heart transplant

http://www.uptodate.com/contents/heart-transplantation-beyond-the-basics uptodate heart transplantation overview

http://www.jhltonline.org/pb/assets/raw/health%20advance/journals/healun/ishlt_guideline.pdf the 2016 international society for heart lung transplantation listing criteria for heart transplantation: a 10-year update by mandeep r. Mehra, md (chair), et al.,

http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/cardiology/heart-transplantation/ cleveland clinic heart transplantation

http://www.medicalnewstoday.com/articles/304757.php medical news today new guidelines for heart transplantation candidacy issued

http://www.itns.org/templates/itnsbasic/pdfs/itns_heart_transplant_booklet.pdf a guide to your health care after heart transplantation

http://www.transmedics.com/wt/page/heart_tx_challenges_pt trans medics challenges of heart transplantation

University of maryland school of medicine. "much longer survival for heart transplants across species: study involved transplanting pig hearts into baboons." sciencedaily. Sciencedaily, 6 april 2016. Www.sciencedaily.com/releases/2016/04/160406140334.htm .

http://patient.info/doctor/cardiac-transplant patient cardiac transplant

https://www.myast.org/sites/default/files/ceot2016/khush_ceot2016.pdf developing a risk score in heart transplantation by kiran k. Khush, md, mas et al.,

Research:

http://www.hindawi.com/journals/sci/2016/9682757/ liangpeng li, xiongwen chen, wei eric wang, and chunyu zeng, “how to improve the survival of transplanted mesenchymal stem cell in ischemic heart?,” stem cells international, vol. 2016, article id 9682757, 14 pages, 2016. Doi:10.1155/2016/9682757

http://www.hindawi.com/journals/cpn/2014/747293/ ike okwuosa, dara pumphrey, jyothy puthumana, rachel-maria brown, and william cotts, “impact of identification and treatment of depression in heart transplant patients,” cardiovascular psychiatry and neurology, vol. 2014, article id 747293, 6 pages, 2014. Doi:10.1155/2014/747293

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0066-782x2000001200005 arq. Bras. Cardiol. Vol.75 n.6 são paulo dec. 2000 http://dx.doi.org/10.1590/s0066-782x2000001200005 pregnancy after cardiac transplantation. Report of one case and review by solange bordignon et al.,

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0066-782x2000000100002 arq. Bras. Cardiol. Vol.74 n.1 são paulo jan. 2000 http://dx.doi.org/10.1590/s0066-782x2000000100002 permanent and temporary pacemaker implantation after orthotopic heart transplantation by fernando bacal et al.,

http://www.pubstemcell.com/monthly/007020400014.htm vol.vii issue: 2: (jsrm code:007020400014) stem cell therapy for congestive heart failure by gunduz e et al.,

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s1807-59322014001300017&lng=en&tlng=enclinics vol.69 supl.1 são paulo 2014 http://dx.doi.org/10.6061/clinics/2014(sup01)04 reviews : challenges with sensitized recipients in pediatric heart transplantation by jennifer conway et al.,

Lang sm, frazier ea, collins r t. Aortic complications following pediatric heart transplantation: a case series and review. Ann pediatr card [serial online] 2016 [cited 2016 aug 2];9:42-5. Available from: http://www.annalspc.com/text.asp?2016/9/1/42/171354

http://www.hindawi.com/journals/bmri/2015/849571/ jatin anand, steve k. Singh, david g. Antoun, william e. Cohn, o. H. (bud) frazier, and hari r. Mallidi, “durable mechanical circulatory support versus organ transplantation: past, present, and future,” biomed research international, vol. 2015, article id 849571, 11 pages, 2015. Doi:10.1155/2015/849571

http://cardiovascularultrasound.biomedcentral.com/articles/10.1186/1476-7120-6-2 usefulness and limitations of transthoracic echocardiography in heart transplantation recipients by sergio mondillo et al, cardiovascular ultrasound20086:2 doi: 10.1186/1476-7120-6-2

http://www.hindawi.com/journals/jtrans/2012/928954/ giuseppe vassalli, giuseppina milano, and tiziano moccetti, “role of mitogen-activated protein kinases in myocardial ischemia-reperfusion injury during heart transplantation,” journal of transplantation, vol. 2012, article id 928954, 16 pages, 2012. Doi:10.1155/2012/928954

http://www.hindawi.com/journals/tswj/2013/364236/ nai-kuan chou, nai-hsin chi, hsi-yu yu, et al., “extracorporeal rescue for early and late graft failure after cardiac transplantation: short result and long-term followup,” the scientific world journal, vol. 2013, article id 364236, 8 pages, 2013. Doi:10.1155/2013/364236

http://www.hindawi.com/journals/bmri/2015/436314/ antonio carlos campos de carvalho and adriana bastos carvalho, “stem cell-based therapies in chagasic cardiomyopathy,” biomed research international, vol. 2015, article id 436314, 5 pages, 2015. Doi:10.1155/2015/436314

http://www.hindawi.com/journals/bmri/2013/387184/ sasitorn yongcharoen, sasivimol rattanasiri, d. Olga mcdaniel, et al., “meta-analysis of cytokine gene polymorphisms and outcome of heart transplantation,” biomed research international, vol. 2013, article id 387184, 8 pages, 2013. Doi:10.1155/2013/387184

http://www.hindawi.com/journals/jtrans/2013/748578/ baskar sekar, pippa j. Newton, simon g. Williams, and steven m. Shaw, “should we consider patients with coexistent hepatitis b or c infection for orthotopic heart transplantation?,” journal of transplantation, vol. 2013, article id 748578, 7 pages, 2013. Doi:10.1155/2013/748578

http://www.nejm.org/doi/full/10.1056/nejmoa010519#t=article effect of sympathetic reinnervation on cardiac performance after heart transplantation by frank m. Bengel, m.d.,et al., n engl j med 2001; 345:731-738september 6, 2001doi: 10.1056/nejmoa010519

http://www.omicsonline.org/ethicality-of-heart-transplantation-from-donation-after-circulatory-death-donors-2155-9880.s9-006.php?aid=14283 ali aa, white c, freed d, ali z, large s (2013) ethicality of heart transplantation from donation after circulatory death donors. J clin exp cardiolog s9:006. Doi: 10.4172/2155-9880.s9-006

Other helpful resources(support groups):

https://www.ishlt.org/guidelines/standardsstatements.asp the international society for heart and lung transplantation

Related videos:

https://www.youtube.com/watch?v=_sdxsjm23_e heart transplantation

https://www.youtube.com/watch?v=qgtlytowtxa complete cardiac transplant

https://www.youtube.com/watch?v=yvesmz53wvm animation of a total heart transplant

https://www.youtube.com/watch?v=n7etgetdcck orthotopic heart transplantation

Presentations/quiz/newspaper articles:

http://www.thehindu.com/news/national/telangana/guntur-ggh-performs-first-heart-transplant/article8628247.eceguntur ggh performs first heart transplant

http://www.bbc.com/news/health-32056350 europe's first non-beating heart transplant

https://www.washingtonpost.com/news/to-your-health/wp/2016/03/02/he-was-about-to-die-on-us-heart-transplant-saves-babys-life/ ‘he was about to die on us': heart transplant saves infant’s life

http://timesofindia.indiatimes.com/city/mumbai/first-heart-transplant-in-mumbai-after-a-gap-of-47-years/articleshow/48336077.cms first heart transplant in mumbai after a gap of 47 years

http://www.newindianexpress.com/states/kerala/kottayam-mch-conducts-second-heart-transplant/2016/04/27/article3401887.ece kottayam mch conducts second heart transplant

http://www.hindustantimes.com/health-and-fitness/why-mumbai-delhi-don-t-have-a-healthy-rate-of-heart-transplants/story-cqdwrlzjc0gra3ks5jsw3n.html why mumbai, delhi don't have a healthy rate of heart transplants