Last Reviewed : 12/25/2020

Endometriosis is a disease in which tissue that normally grows inside the uterus grows outside it.The main symptoms are pelvic pain and infertility. Nearly half of those affected have chronic pelvic pain, while in 70% pain occurs during menstruation. Pain during sex is also common. Infertility occurs in up to half of women affected.Less common symptoms include urinary or bowel symptoms. About 25% of women have no symptoms. Endometriosis can have both social and psychological effects.

The cause is not entirely clear.Risk factors include having a family history of the condition. Most often the ovaries, fallopian tubes, and tissue around the uterus and ovaries are affected; however, in rare cases it may also occur in other parts of the body. The areas of endometriosis bleed each month, resulting in inflammation and scarring.The growths due to endometriosis are not cancer. Diagnosis is usually based on symptoms in combination with medical imaging. Biopsy is the most sure method of diagnosis.Other causes of similar symptoms include irritable bowel syndrome, interstitial cystitis, and fibromyalgia.

Tentative evidence suggests that the use of combined oral contraceptives reduces the risk of endometriosis.Exercise and avoiding large amounts of alcohol may also be preventative. There is no cure for endometriosis, but a number of treatments may improve symptoms.This may include pain medication, hormonal treatments, or surgery. The recommended pain medication is usually anNSAID such as naproxen. Taking the active component of the birth control pill continuously or using an intrauterine device with progestogen may also be useful. Gonadotropin-releasing hormone agonist may improve the ability of those who are infertile to get pregnant. Surgical removal of endometriosis may be used to treat those whose symptoms are not manageable with other treatments.

Endometriosis is estimated to occur in roughly 6–10% of women. It is most common in those in their thirties and forties. It results in few deaths with this being estimated at 200 globally in 2013. Endometriosis was first determined to be a separate condition in the 1920s. Before that time endometriosis and adenomyosis were considered together. It is unclear who first described the disease.


We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.


Basic information:

http://www.medicinenet.com/endometriosis/article.htm medicine net endometriosis

http://www.healthline.com/health/endometriosis health line endometriosis

http://www.webmd.com/women/endometriosis/ web md endometriosis

http://www.mayoclinic.org/diseases-conditions/endometriosis/basics/definition/con-20013968 mayo clinic endometriosis definition

http://www.endometriosisassn.org/endo.html enometriosis association endometriosis

http://www.endofound.org/endometriosis endometriosis foundation of america what is endometriosis?

https://www.nlm.nih.gov/medlineplus/endometriosis.html medline plus endometriosis

http://www.nhs.uk/conditions/endometriosis/pages/introduction.aspx nhs uk endometriosis

http://www.endometriosis.ie/about-endometriosis/endometriosis-symptoms/ endometriosis association of ireland endometriosis

http://www.hopkinsmedicine.org/healthlibrary/conditions/gynecological_health/endometriosis_85,p00573/ hopkins medicine endometriosis

http://americanpregnancy.org/womens-health/endometriosis/ american pregnancy.org endometriosis

http://kidshealth.org/en/teens/endometriosis.html kids health .org endometriosis

http://www.netdoctor.co.uk/conditions/sexual-health/a11642/endometriosis/ net doctor endometriosis

https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/endometriosis better health endometriosis

https://www.merckmanuals.com/professional/gynecology-and-obstetrics/endometriosis/endometriosis merck manuals (professional version) endometriosis

http://www.bupa.co.uk/health-information/directory/e/endometriosis bupa endometriosis

http://www.healthdirect.gov.au/endometriosis health direct endometriosis

https://www.verywell.com/what-is-endometriosis-1959928 very well what is endometriosis? How might it cause infertility?

http://www.emedicinehealth.com/endometriosis/article_em.htm emedicine health endometriosis

https://www.southerncross.co.nz/group/medical-library/endometriosis-symptoms-diagnosis-surgery-treatmentsouthern cross medical library endometriosis - symptoms, diagnosis, surgery, treatment


Advanced information:

http://patient.info/health/endometriosis-leaflet patient endometriosis

http://emedicine.medscape.com/article/271899-overview medscape endometriosis

http://www.medicalnewstoday.com/articles/149109.php mnt endometriosis

http://www.advancedfertility.com/endometriosis.htm advanced fertility center of chicago the effect of endometriosis on fertility and infertility

http://radiopaedia.org/articles/endometriosis radiopedia endometriosis

http://my.clevelandclinic.org/health/diseases_conditions/hic_endometriosis/hic_surgical_treatment_for_endometriosissurgical treatment for endometriosis



http://www.sciencedirect.com/science/article/pii/s2210261213003283 primary umbilical endometriosis. Case report and discussion on management options by alessandro fancellu et al., international journal of surgery case reports volume 4, issue 12, 2013, pages 1145–1148 doi:10.1016/j.ijscr.2013.11.001

http://www.bioline.org.br/request?mf12011 evidence based medicine corner evidence based surgical management of endometriosis by mohamed a. Bedaiwy , nichole m. Barker et al., middle east fertility society journal (2012) 17, 57–60

http://www.hindawi.com/journals/criog/2015/534273/ case reports in obstetrics and gynecology
volume 2015 (2015), article id 534273, 4 pages http://dx.doi.org/10.1155/2015/534273 case report:endometrial stromal sarcoma arising in colorectal endometriosis: a case report and review of the literature by qiao wang, xia zhao, and ping han

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0104-42302016000100072&lng=en&tlng=en rev. Assoc. Med. Bras. Vol.62 no.1 são paulo jan./feb. 2016 http://dx.doi.org/10.1590/1806-9282.62.01.72 review articles:estrogen signaling in the proliferative endometrium: implications in endometriosis by rita de cássia pereira da costa e silva et al.,

http://www.hindawi.com/journals/criog/2013/386783/ case reports in obstetrics and gynecology
volume 2013 (2013), article id 386783, 4 pages http://dx.doi.org/10.1155/2013/386783 case report scar endometriosis: a case report of this uncommon entity and review of the literature by cihangir uzunçakmak, ahmet güldas, hasene özçam, and kemal dinç

http://rbej.biomedcentral.com/articles/10.1186/1477-7827-9-89 use of aromatase inhibitors to treat endometriosis-related pain symptoms: a systematic review by simone ferrero,david j gillott,pier l venturini and valentino remorgida reproductive biology and endocrinology20119:89 doi: 10.1186/1477-7827-9-89

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s2237-93632012000300020 j. Coloproctol. (rio j.) Vol.32 no.3 rio de janeiro july/sept. 2012 http://dx.doi.org/10.1590/s2237-93632012000300020 case report:appendiceal endometriosis as a rare cause of abdominal pain – a case report and literature review by rafael denadai et al.,

http://www.hindawi.com/journals/isrn/2011/140310/ isrn obstetrics and gynecology
volume 2011 (2011), article id 140310, 6 pages http://dx.doi.org/10.5402/2011/140310 review article:endometriosis and ovarian cancer: a systematic review by ahmad sayasneh, dimitris tsivos, and robin crawford

http://f1000research.com/articles/5-186/v1 nothnick w and alali z. Recent advances in the understanding of endometriosis: the role of inflammatory mediators in disease pathogenesis and treatment [version 1; referees: 4 approved]. F1000research2016, 5(f1000 faculty rev):186 (doi: 10.12688/f1000research.7504.1)

http://www.scielo.br/scielo.php?script=sci_arttext&pid=s0104-42302015000600519&lng=en&tlng=en rev. Assoc. Med. Bras. Vol.61 no.6 são paulo nov./dec. 2015 http://dx.doi.org/10.1590/1806-9282.61.06.519 review articles:nutritional aspects related to endometriosis by gabriela halpern et al.,

http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501200027u.pdf acute small bowel obstruction due to ileal endometriosis: a case report and review of the most recent literature by haluk recai unalp et al., vojnosanit pregl 2012; 69(11): 1013–1016

Kumar s, tiwari p, sharma p, goel a, singh jp, vijay mk, gupta s, bera mk, kundu ak. Urinary tract endometriosis: review of 19 cases. Urol ann [serial online] 2012 [cited 2016 jun 9];4:6-12. Available from: http://www.urologyannals.com/text.asp?2012/4/1/6/91613

http://www.hindawi.com/journals/criu/2013/812475/ case reports in urology
volume 2013 (2013), article id 812475, 5 pages http://dx.doi.org/10.1155/2013/812475 case report:lumbar ureteral stenosis due to endometriosis: our experience and review of the literature by salvatore butticè et al,


Related topics:

http://www.itmonline.org/journal/arts/endometriosis.htm chinese herbal therapy for endometriosis
by subhuti dharmananda, ph.d., director, institute for traditional medicine, portland, oregon internet journal of the institute for traditional medicine and preventive health care


Other helpful resources(support groups):

http://endometriosisfoundation.org/ world endometriosis research foundation


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