Endocarditis is an inflammation of the inner layer of the heart, the endocardium, usually involving the heart valves. There are two types based on cause: either infective or non-infective, depending on whether a microorganism is the source of the inflammation or not. Signs and symptoms include: fever, chills, sweating, malaise, weakness, anorexia, weight loss, splenomegaly, flu-like feeling, cardiac murmur, heart failure, petechia of anterior trunk, Janeway's lesions, etc. Endocarditis is more common in men than women. Children with congenital heart defects can also develop endocarditis. 13 out of every 100,000 people in the United States are hospitalized with infective endocarditis each year. The average age of people hospitalized with endocarditis is about 60 years old.
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