Creutzfeldt–Jakob disease (CJD) is a Neurodegenerative disease that is incurable and invariably fatal. CJD is at times called a human form of mad cow disease (bovine spongiform encephalopathy or BSE). However, given that BSE is believed to be the cause of Variant Creutzfeldt–Jakob disease (vCJD) in humans, the two are often confused.
CJD is caused by an infectious agent called a prion. Prions are misfolded proteins that replicate by converting their properly folded counterparts, in their host, to the same misfolded structure they possess. CJD causes the brain tissue to degenerate rapidly, and as the disease destroys the brain, the brain develops holes and the texture changes to resemble that of a kitchen sponge.
We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.
Basic information:
http://www.ninds.nih.gov/disorders/cjd/detail_cjd.htm national institute of neurological disorders and stroke creutzfeldt-jakob disease
http://www.mayoclinic.org/diseases-conditions/creutzfeldt-jakob-disease/basics/definition/con-20028005 mayo clinic creutzfeldt jakob disease
http://www.nhs.uk/conditions/creutzfeldt-jakob-disease/pages/introduction.aspx nhs uk creutzfeldt jakob disease
http://www.nhs.uk/conditions/creutzfeldt-jakob-disease/pages/causes.aspx nhs uk causes of creutzfeldt-jakob disease
http://www.livescience.com/34717-creutzfeldt-jakob-disease.html live science creutzfeldt-jakob disease: symptoms, diagnosis and treatment
https://medlineplus.gov/ency/article/000788.htm medline plus creutzfeldt-jakob disease
http://www.webmd.com/brain/mad-cow-disease-basics#1 web md the basics of mad cow disease
http://www.healthline.com/health/creutzfeldt-jakob-disease health line creutzfeldt-jakob disease and mad cow disease
https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/creutzfeldt-jakob-disease-cjd better health creutzfeldt-jakob disease (cjd)
http://bodyandhealth.canada.com/condition/getcondition/creutzfeldt-jakob-disease body and health creutzfeldt-jakob disease
https://www.healthlinkbc.ca/healthlinkbc-files/creutzfeldt-jakob-disease health link bc creutzfeldt-jakob disease (cjd)
http://www.merckmanuals.com/professional/neurologic-disorders/prion-diseases/creutzfeldt-jakob-disease-cjd merck manuals (professional version) creutzfeldt-jakob disease (cjd)
http://my.clevelandclinic.org/services/neurological_institute/lou-ruvo-brain-health/brain-health-diseases-conditions/creutzfeldt-jakob-disease cleveland clinic creutzfeldt jakob disease
http://www.nytimes.com/health/guides/disease/creutzfeldt-jakob-disease/overview.html new york times creutzfeldt jakob disease
https://www.verywell.com/creutzfeldt-jakob-disease-p2-98734 very well how creutzfeldt-jakob disease differs from alzheimer's
Advanced information:
http://www.who.int/mediacentre/factsheets/fs180/en/ who variant creutzfeldt-jakob disease
http://www.medicalnewstoday.com/articles/185884.php medical news today what is creutzfeldt-jakob disease (cjd)?
http://emedicine.medscape.com/article/1169688-overview medscape variant creutzfeldt-jakob disease and bovine spongiform encephalopathy
https://radiopaedia.org/articles/creutzfeldt-jakob-disease radiopedia creutzfeldt-jakob disease
http://patient.info/doctor/creutzfeldt-jakob-disease patient creutzfeldt-jakob disease
http://www.emedicinehealth.com/mad_cow_disease_and_variant_creutzfeldt-jakob/article_em.htm emedicine health mad cow disease and variant creutzfeldt-jakob disease
Research:
http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-4-26 epidemiological evidence of higher susceptibility to vcjd in the young by pierre-yves boëlle et al., bmc infectious diseases20044:26 doi: 10.1186/1471-2334-4-26
Singhal b s. Creutzfeldt-jacob disease (cjd) : report of 10 cases from north india. Neurol india [serial online] 2002 [cited 2016 nov 28];50:113. Available from: http://www.neurologyindia.com/text.asp?2002/50/1/113/1342
Kumaran sp, gupta k, pushpa b t, viswamitra s, joshy e v. Diffusion-weighted imaging: as the first diagnostic clue to creutzfeldt jacob disease. J neurosci rural pract [serial online] 2012 [cited 2016 nov 28];3:408-10. Available from: http://www.ruralneuropractice.com/text.asp?2012/3/3/408/102645
Gadgil nm, chaudhari cs, gohil sd, kalgutkar ad. Creutzfeldt-jacob disease: an autopsy case report in tertiary care hospital. Indian j pathol microbiol [serial online] 2012 [cited 2016 nov 28];55:97-9. Available from: http://www.ijpmonline.org/text.asp?2012/55/1/97/94871
Kumaran sp, gupta k, pushpa b t, viswamitra s, joshy e v. Diffusion-weighted imaging: as the first diagnostic clue to creutzfeldt jacob disease. J neurosci rural pract [serial online] 2012 [cited 2016 nov 28];3:408-10. Available from: http://www.ruralneuropractice.com/text.asp?2012/3/3/408/102645
Prabhakar s, bhatia r. Diagnosis of creutzfeldt - jacob disease. Neurol india [serial online] 2001 [cited 2016 nov 28];49:325. Available from: http://www.neurologyindia.com/text.asp?2001/49/4/325/1226
Praveen k s, sinha s, chandrasekhar h s, vijayan j, taly a b. Sporadic onset creutzfeldt-jacob disease: interesting mri observations. Neurol india [serial online] 2006 [cited 2016 nov 28];54:418-20. Available from: http://www.neurologyindia.com/text.asp?2006/54/4/418/28119
Mehndiratta m m, bajaj b k, gupta m, anand r, tatke m, seryam s, nehru r, puri v, khwaja g a. Creutzfeldt-jakob disease : report of 10 cases from north india. Neurol india [serial online] 2001 [cited 2016 nov 29];49:338. Available from: http://www.neurologyindia.com/text.asp?2001/49/4/338/1224
http://www.nejm.org/doi/full/10.1056/nejmoa1315200#t=article a test for creutzfeldt–jakob disease using nasal brushings by christina d. Orrú, ph.d. Et al., n engl j med 2014; 371:519-529august 7, 2014doi: 10.1056/nejmoa1315200
http://bmcneurol.biomedcentral.com/articles/10.1186/1471-2377-11-133 diagnostic accuracy of cerebrospinal fluid protein markers for sporadic creutzfeldt-jakob disease in canada: a 6-year prospective study by michael b coulthart et al., bmc neurology201111:133 doi: 10.1186/1471-2377-11-133
http://www.ajnr.org/content/26/6/1551.full diffusion-weighted and fluid-attenuated inversion recovery imaging in creutzfeldt-jakob disease: high sensitivity and specificity for diagnosis by geoffrey s. Young et al., ajnr 2005 26: 1551-1562
Akehurst c. New variant creutzfeldt-jakob disease and the safety of blood and blood products. Euro surveill. 1997;1(30):pii=1020. Available online: http://www.eurosurveillance.org/viewarticle.aspx?articleid=1020
Other helpful resources(support groups):
https://www.alz.org/dementia/creutzfeldt-jakob-disease-cjd-symptoms.asp alzheimers association
https://www.cjdfoundation.org/ cjd foundation
http://www.cjdsupport.net/ cjd support
Related videos:
https://www.youtube.com/watch?v=dau1lx7g6ha creutzfeldt-jakob disease (cjd)
https://www.youtube.com/watch?v=z8_j7ftlxiw what is creutzfeldt jakob disease (cjd)?
https://www.youtube.com/watch?v=ogjt0nhgwd4 creutzfeldt-jakob disease (cjd) - sporadic cjd
https://www.youtube.com/watch?v=bwnvonjdfxi what is creutzfeldt-jakob (cjd) disease?
https://www.youtube.com/watch?v=5rxxersn1eo creutzfeldt jakob disease
Presentations/quiz/newspaper articles:
http://theconversation.com/rare-and-deadly-creutzfeldt-jakob-disease-remains-a-bit-of-a-medical-mystery-44408 the conversation rare and deadly, creutzfeldt-jakobdisease remains a bit of a medical mystery
http://www.upi.com/health_news/2016/10/04/urine-test-may-detect-creutzfeldt-jakob-disease/6701475582552/ upi urine test may detect creutzfeldt-jakob disease
http://www.express.co.uk/life-style/health/666554/reheating-rice-food-poisoning express how reheating rice can be more toxic than uncooked meat: the deadly danger in leftovers