Pulmonary heart disease, also known as cor pulmonale is the enlargement and failure of the right ventricle of the heart as a response to increased vascular resistance (such as from pulmonic stenosis) or high blood pressure in the lungs
Chronic pulmonary heart disease usually results in right ventricular hypertrophy (RVH), whereas acute pulmonary heart disease usually results in dilatation. Hypertrophy is an adaptive response to a long-term increase in pressure. Individual muscle cells grow larger (in thickness) and change to drive the increased contractile force required to move the blood against greater resistance. Dilatation is a stretching (in length) of the ventricle in response to acute increased pressure.
To be classified as pulmonary heart disease, the cause must originate in the pulmonary circulation system. Two causes are vascular changes as a result of tissue damage (e.g. disease, hypoxic injury), and chronic hypoxic pulmonary vasoconstriction. If left untreated, then death may result, RVH due to a systemic defect is not classified as pulmonary heart disease. The heart and lungs are intricately related; whenever the heart is affected by disease, the lungs will follow and vice versa. Pulmonary heart disease is by definition a condition when the lungs cause the heart to fail.
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https://www.hindawi.com/journals/tswj/2012/757283/ pi-chang lee, betau hwang, wen-jue soong, and c. C. Laura meng, “the specific characteristics in children with obstructive sleep apnea and cor pulmonale,” the scientific world journal, vol. 2012, article id 757283, 6 pages, 2012. Doi:10.1100/2012/757283
http://www.jemds.com/data_pdf/naveen%20n.pdf sunil babu m, praveen n, vasudev naik. “a study of clinical profile, radiological features, electrocardiographic and echocardiographic changes in chronic cor pulmonale in a rural hospital”. Journal of evolution of medical and dental sciences 2013; vol. 2, issue 45, nov ember 11; page: 8827-8840.
Fawibe ae, kolo pm, ogunmodede ja, desalu oo, salami ka. Advanced sickle cell associated interstitial lung disease presenting with cor pulmonale in a nigerian. Niger med j [serial online] 2012 [cited 2016 aug 31];53:105-7. Available from: http://www.nigeriamedj.com/text.asp?2012/53/2/105/103552
Patra s, chatterjee s, singhla s, patra b, maheswari a, seth a. Cor pulmonale in a case of infantile gaucher's disease. Indian j endocr metab [serial online] 2011 [cited 2016 aug 31];15:134-6. Available from: http://www.ijem.in/text.asp?2011/15/2/134/81948
https://www.hindawi.com/journals/cripe/2012/836420/ john m. Holst and mary j. Willis, “a fatal case of cor pulmonale with undetected chronic hypoventilation in an infant with a known congenital myopathy,” case reports in pediatrics, vol. 2012, article id 836420, 4 pages, 2012. Doi:10.1155/2012/836420