Cluster headache

Cluster headache

Last Reviewed : 12/25/2020
Cluster headache

Cluster headache (CH) is a neurological disorder characterized by recurrent, severe headaches on one side of the head, typically around the eye. There are often accompanying autonomic symptoms during the headache such as eye watering,nasal congestion and swelling around the eye, typically confined to the side of the head with the pain.

Cluster headache belongs to a group of primary headache disorders, classified as the trigeminal autonomic cephalalgias or (TACs). Cluster headache is named after the demonstrated grouping of headache attacks occurring together (cluster). Individuals typically experience repeated attacks of excruciatingly severe unilateral headache pain. Cluster headache attacks often occur periodically; spontaneous remissions may interrupt active periods of pain, though about 10–15% of chronic CH never remit.[2] The cause of cluster headache has not been identified.

While there is no known cure, cluster headaches can sometimes be prevented and acute attacks treated. Recommended treatments for acute attacks include oxygen or a fast acting triptan. Primary recommended prevention is verapamil. Steroids may be used as a transitional treatment and may prevent attack recurrence until preventative treatments take effect. The condition affects approximately 0.2% of the general population, and men are more commonly affected than women, by a ratio of about 2.5:1 to 3.5:1.


We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.


Basic information: web md cluster headaches mayoclinic cluster headache nhs uk cluster headache headache australia cluster headache everyday health is it a migraine or a cluster headache? medline plus cluster headache health line cluster headache merck manuals(professional version) cluster headache health direct cluster headache health link bc cluster headache new york times cluster headache health central cluster headaches - the basics university of maryland medical center cluster headache


Advanced information: medscape cluster headache medicine net cluster headache patuent cluster headache emedicine health cluster headache medical news today cluster headaches: causes, symptoms and diagnosis cluster cluster headache cluster headache by jacqueline weaver-agostoni, do, mph, university of pittsburgh medical center shadyside hospital, pittsburgh, pennsylvania am fam physician. 2013 jul 15;88(2):122-128. national organisation for are diseases cluster headache aetna migraine and cluster headache: nonsurgical management



Bhargava a, pujar gs, banakar bf, shubhakaran, kasundra g, bhushan b. Study of cluster headache: a hospital-based study. J neurosci rural pract [serial online] 2014 [cited 2016 dec 29];5:369-73. Available from: : qiu e, wang y, ma l, tian l, liu r, et al. (2013) abnormal brain functional connectivity of the hypothalamus in cluster headaches. Plos one 8(2):e57896. Doi:10.1371/journal.pone.0057896 arq. Neuro-psiquiatr. Vol.65 no.2a são paulo june 2007 cluster headache attacks in a woman previously struck by lightning: pathophysiology of the latent period by marcelo moraes valença et al.,

Prasad p, subramanya r, upadhyaya n s. Cluster headache or narrow angle glaucoma?. Indian j ophthalmol [serial online] 1991 [cited 2016 dec 29];39:181-2. Available from: arq. Neuro-psiquiatr. Vol.71 no.11 são paulo nov. 2013 articles:familial aggregation of cluster headache by simão cruz et al., enucleation and development of cluster headache: a retrospective study by peter sörös et al., bmc neurology20055:6 doi: 10.1186/1471-2377-5-6

Datta ss, kumar s. Clozapine-responsive cluster headache. Neurol india [serial online] 2006 [cited 2016 dec 29];54:200-1. Available from:

Huang w y, lo m c, wang s j, tsai j j, wu h m. Topiramate in prevention of cluster headache in the taiwanese. Neurol india [serial online] 2010 [cited 2016 dec 29];58:284-7. Available from: cluster headache by elizabeth leroux and anne ducros orphanet journal of rare diseases20083:20 doi: 10.1186/1750-1172-3-20 cluster headache with ptosis responsive to intranasal lidocaine application: a case report by berker bakbak et al., journal of medical case reports20126:64 doi: 10.1186/1752-1947-6-64 m. J. Levy, i. Robertson, and t. A. Howlett, “cluster headache secondary to macroprolactinoma with ipsilateral cavernous sinus invasion,” case reports in neurological medicine, vol. 2012, article id 830469, 3 pages, 2012. Doi:10.1155/2012/830469 central modulation in cluster headache patients treated with occipital nerve stimulation: an fdg-pet study by delphine magis et al., bmc neurology201111:25 doi: 10.1186/1471-2377-11-25


Other helpful resources(support groups): the migrain trust organisation for the understanding of cluster headache cluster headache foundation


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Presentations/quiz/newspaper articles: the atlantic cluster headaches: the worst possible pain? the daily beast longtime sufferers of cluster headaches find relief in psychedelics psychedelic mushrooms cured my cluster headaches daily mail ask the doctor: why is my nose blocked or runny all the time?

Read more: the guardian cluster headache

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