Chronic respiratory failure (CRF) is a long-term condition that happens when lungs cannot get enough oxygen into blood. Heart, brain, and other organs depend on the oxygen in blood to work properly. CRF can also happen when lungs cannot get the carbon dioxide out of blood. A buildup of carbon dioxide in blood can cause damage to organs. The decrease in oxygen and the buildup of carbon dioxide can happen at the same time. CRF may develop over a period of days to years and requires long-term treatment.
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