Neuropathic arthropathy (or neuropathic osteoarthropathy), also known as Charcot joint (often "Charcot foot"), refers to progressive degeneration of a weight bearing joint, a process marked by bony destruction, bone resorption, and eventual deformity. Onset is usually insidious.
If this pathological process continues unchecked, it can result in joint deformity, ulceration and/or superinfection, loss of function, and in the worst-case scenario, amputation or death. Early identification of joint changes is the best way to limit morbidity.
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http://www.aafp.org/afp/2001/1101/p1591.html charcot foot: the diagnostic dilemma todd c. Sommer, d.o., d.p.m., prevea health system, green bay, wisconsin.,thomas h. Lee, m.d., ohio state university college of medicine, columbus, ohio am fam physician. 2001 nov 1;64(9):1591-1598.
http://www.aafp.org/afp/1998/0601/p2705.html the charcot foot in diabetes: six key points gregory m. Caputo, m.d., jan ulbrecht, m.d., peter r. Cavanagh, ph.d., and paul juliano, m.d., milton s. Hershey medical center and pennsylvania state university, hershey, pennsylvania am fam physician. 1998 jun 1;57(11):2705-2710.
Shah ns, de sd. Comparative analysis of uniplanar external fixator and retrograde intramedullary nailing for ankle arthrodesis in diabetic charcot's neuroarthropathy. Indian j orthop [serial online] 2011 [cited 2016 nov 28];45:359-64. Available from: http://www.ijoonline.com/text.asp?2011/45/4/359/82343
Vemula vr, bodapati cp, vuttarkar j, vosuri bb. Bilateral ulnar neuropathy at the elbow secondary to charcot-joint associated with chiari malformation and syringomyelia. Neurol india [serial online] 2016 [cited 2016 nov 28];64:1099-100. Available from: http://www.neurologyindia.com/text.asp?2016/64/5/1099/190297
https://www.hindawi.com/journals/crinm/2015/487931/ roya memarpour, basheer tashtoush, lydia issac, and fernando gonzalez-ibarra, “syringomyelia with chiari i malformation presenting as hip charcot arthropathy: a case report and literature review,” case reports in neurological medicine, vol. 2015, article id 487931, 6 pages, 2015. Doi:10.1155/2015/487931
https://www.hindawi.com/journals/crior/2014/760861/ cuneyd gunay, ebru atalar, and baybars ataoglu, “an unusual presentation of charcot arthropathy caused by syringomyelia mimicking a soft tissue tumor,” case reports in orthopedics, vol. 2014, article id 760861, 4 pages, 2014. Doi:10.1155/2014/760861