Carbon monoxide poisoning

Carbon monoxide poisoning

Last Reviewed : 12/24/2020
Carbon monoxide poisoning

Carbon monoxide poisoning occurs after too much inhalation of carbon monoxide (CO). Carbon monoxide is a toxic (poisonous) gas, but, being colorless, odorless, tasteless, and initially non-irritating, it is very difficult for people to detect. Carbon monoxide is a product of incomplete combustion of organic matter due to insufficient oxygen supply to enable complete oxidation to carbon dioxide(CO2). It is often produced in domestic or industrial settings by motor vehicles that run on gasoline, diesel, methane, or other carbon-based fuels and from tools, gas heaters, and cooking equipment that are powered by carbon-based fuels such as propane, butane and charcoal. Exposure at 100 ppm or greater can be dangerous to human health.

Symptoms of mild acute poisoning include lightheadedness, confusion, headache, vertigo, and flu-like effects; larger exposures can lead to significant toxicity of the central nervous system and heart, and death. After acute poisoning, long-term sequelae often occur. Carbon monoxide can also have severe effects on the fetus of a pregnant woman. Chronic exposure to low levels of carbon monoxide can lead to depression, confusion, and memory loss. Carbon monoxide mainly causes adverse effects in humans by combining with hemoglobin to form carboxyhemoglobin (HbCO) in the blood. This prevents hemoglobin from carrying oxygen to the tissues, effectively reducing the oxygen-carrying capacity of the blood, leading to hypoxia. Additionally, myoglobin and mitochondrialcytochrome oxidase are thought to be adversely affected. Carboxyhemoglobin can revert to hemoglobin, but the recovery takes time because the HbCO complex is fairly stable.

Treatment of poisoning largely consists of administering 100% oxygen or providing hyperbaric oxygen therapy, although the optimum treatment remains controversial. Oxygen works as an antidote as it increases the removal of carbon monoxide from hemoglobin, in turn providing the body with normal levels of oxygen. The prevention of poisoning is a significant public health issue. Domestic carbon monoxide poisoning can be prevented by early detection with the use of household carbon monoxide detectors. Carbon monoxide poisoning is the most common type of fatal poisoning in many countries. Historically, it was also commonly used as a method to commit suicide, usually by deliberately inhaling the exhaust fumes of a running car engine. Modern automobiles, even with electronically controlled combustion and catalytic converters, can still produce levels of carbon monoxide which will kill if enclosed within a garage or if the tailpipe is obstructed (for example, by snow) and exhaust gas cannot escape normally. Carbon monoxide poisoning has also been speculated as a possible cause of apparent haunted houses; symptoms such as delirium and hallucinations may have led people suffering poisoning to think they have seen ghosts or to believe their house is haunted.


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Basic information: carbon monoxide poisoning carbon monoxide poisoning health line carbon monoxide poisoning carbon monoxide poisoning medline plus carbon monoxide poisoning msd manuals(professional version) carbon monoxide poisoning my health carbon monoxide poisoning healthy how to prevent carbon monoxide poisoning medicine carbon monoxide poisoning new york times carbon monoxide poisoning


Advanced information: medscape carbon monoxide toxicity emedicine health carbon monoxide poisoning carbon carbon monoxide poisoning patient carbon monoxide poisoning silent shadow:silent killer long term effects of carbon monoxide poisoning us environment protection agency carbon monoxide's impact on indoor air quality national fire protection association carbon monoxide britannica carbon monoxide poisoning carbon monoxide poisoning net carbon monoxide poisoning under sea and hyperbaric medical society carbon monoxide poisoning life in the fast lane carbon monoxide poisoning radiopedia carbon monoxide poisoning family practise notebook carbon monoxide poisoning mnt carbon monoxide poisoning


el sayed mj, tamim h. Carbon monoxide poisoning in beirut, lebanon: patient's characteristics and exposure sources. J emerg trauma shock 2014;7:280-4 j. Bras. Pneumol. Vol.39 no.3 são paulo may/june 2013 review article:smoke inhalation injury during enclosed-space fires: an update* by ana carolina peçanha antonio et al.,;year=2014;volume=58;issue=3;spage=350;epage=352;aulast=sekhar sekhar k c, rao sc. John scott haldane: the father of oxygen therapy. Indian j anaesth 2014;58:350-2 asia pacific journal of medical toxicology apjmt 2;2 june 2013 an outbreak of carbon monoxide poisoning in yamagata prefecture following the great east japan earthquake by ken iseki et al., comparison of carbon monoxide poisonings originated from coal stove and natural gas and the evaluation of neutrophil/lymphocyte ratio by yahya kemal günaydinet al., 2015; 42 (3): 299-304 dicle medical journal doi: 10.5798/diclemedj.0921.2015.03.0578 scientifica
volume 2016 (2016), article id 6192369, 4 pages research article:utility of the measurement of carboxyhemoglobin level at the site of acute carbon monoxide poisoning in rural areas by makoto onodera et al.,;year=2014;volume=7;issue=4;spage=280;epage=284;aulast=elel sayed mj, tamim h. Carbon monoxide poisoning in beirut, lebanon: patient's characteristics and exposure sources. J emerg trauma shock 2014;7:280-4 case reports in pediatrics
volume 2012 (2012), article id 231230, 3 pages case report:sensorineural hearing loss following carbon monoxide poisoning by joseph p. Pillion;year=2008;volume=11;issue=4;spage=251;epage=253;aulast=subhaschandra subhaschandra s, jatishwor w, th.suraj. Isolated symmetrical bilateral basal ganglia t2 hyperintensity in carbon monoxide poisoning. Ann indian acad neurol 2008;11:251-3;year=2007;volume=11;issue=2;spage=80;epage=82;aulast=bhatiabhatia r, chacko f, lal v, mittal b r. Reversible delayed neuropsychiatric syndrome following acute carbon monoxide exposure. Indian j occup environ med 2007;11:80-2 status epilepticus and cardiopulmonary arrest in a patient with carbon monoxide poisoning with full recovery after using a neuroprotective strategy: a case report by salman abdulaziz et al., journal of medical case reports20126:421 doi: 10.1186/1752-1947-6-421 © abdulaziz et al;year=2009;volume=13;issue=3;spage=169;epage=170;aulast=sharma sharma s, gupta r, paul bs, puri s, garg s. Accidental carbon monoxide poisoning in our homes. Indian j crit care med 2009;13:169-70 volume 2013 (2013), article id 940187, 3 pages case report:hearing loss due to carbon monoxide poisoning by amir houshang mehrparvar et al., hyperbaric oxygen for acute carbon monoxide poisoning by lindell k. Weaver n engl j med 2002; 347:1057-1067october 3, 2002doi: 10.1056/nejmoa013121


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Presentations/quiz/newspaper articles: i thought i had early dementia but for three years i was poisoned by carbon monoxide 4 people, 1 dog killed in apparent carbon monoxide poisoning at wilmington apartment building the cause of the carbon monoxide buildup was not yet known by vince lattanzio at least 6 die of carbon monoxide poisoning after massive snowstorm at least 13 people treated for carbon monoxide poisoning posted 4:11 am, february 17, 2016, by darren sweeney, updated at 10:10am, february 17, 2016 carbon monoxide potential cause behind death of family of six

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