Aortic stenosis

Aortic stenosis

Last Reviewed : 12/24/2020
Aortic stenosis

Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart, such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occurs due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercise. Signs of heart failure include shortness of breath especially when lying down, at night, or with exercise, and swelling of the legs. Thickening of the valve without narrowing is known as aortic sclerosis.

Causes include being born with a bicuspid aortic valve and rheumatic fever. A bicuspid aortic valve affects about one to two percent of the population while rheumatic heart disease mostly occurring in the developing world. A normal valve, however, may also harden over the decades. Risk factors are similar to those of coronary artery disease and include smoking, high blood pressure, high cholesterol, diabetes, and being male. The aortic valve usually has three leaflets and is located between the left ventricle of the heartand the aorta. AS typically results in a heart murmur. Its severity can be divided into mild, moderate, severe, and very severe based on ultrasound of the heart findings.


We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.


Basic information: medline plus aortic stenosis problem: aortic valve stenosis mayoclinic anthrax web md aortic valve stenosis - topic overview health line aortic valve stenosis better health aortic stenosis nhs uk aortic valve replacement - why it's done new york times aortic stenosis very well aortic stenosis


Advanced information: patient aortic stenosis medicine net anthrax medscape anthrax cleveland clinic aortic valve disease aortic stenosis: diagnosis and treatment brian h. grimard, md; robert e. safford, md, phd; and elizabeth l. burns, md, mayo medical school, jacksonville, florida am fam physician. 2016 mar 1;93(5):371-378. genetics home reference supravalvular aortic stenosis healio aortic valve stenosis radiopedia aortic valve stenosis

university of pennsylvania school of medicine. "one-third of patients with low flow aortic stenosis do not improve with transcatheter aortic valve replacement, research finds: patients who do not improve with tavr are found to have worse clinical outcomes at one year." sciencedaily. sciencedaily, 15 june 2016. . types of aortic valve disease


Research: nitroprusside in critically ill patients with left ventricular dysfunction and aortic stenosis by umesh n. khot, m.d n engl j med 2003; 348:1756-1763may 1, 2003doi: 10.1056/nejmoa022021 aortic stenosis: pathophysiology,diagnosis, and medical management of nonsurgical patients theresa cary, rn, msn, acns-bc, ccrn, chfn judith pearce, rn, bsn, ccrn surgery for severe aortic stenosis with low transvalvular gradient and poor left ventricular function – a single centre experience and review of the literature by andreas borowski et al., journal of cardiothoracic surgery20072:9 doi: 10.1186/1749-8090-2-9 transcatheter aortic valve replacement: a review article by juan a siordia et al., j cardiothorac med. 2016; 4(2):423-436. katie l. losenno, robert l. goodman, and michael w. a. chu, “bicuspid aortic valve disease and ascending aortic aneurysms: gaps in knowledge,” cardiology research and practice, vol. 2012, article id 145202, 16 pages, 2012. doi:10.1155/2012/145202 epidemiology and cardiovascular risk factors of aortic stenosis by pompilio faggiano et al., cardiovascular ultrasound20064:27 doi: 10.1186/1476-7120-4-27

franco a, gerli c, ruggeri l, monaco f. anesthetic management of transcatheter aortic valve implantation. ann card anaesth [serial online] 2012 [cited 2016 jul 29];15:54-63. available from: hyperdominant left anterior descending artery continuing across left ventricular apex as posterior descending artery coexistent with aortic stenosis by kalyana javangula and pankaj kaul journal of cardiothoracic surgery20072:42 doi: 10.1186/1749-8090-2-42 afshar ah, pourafkari l, nader nd. periprocedural considerations of transcatheter aortic valve implantation for anesthesiologists. j cardiovasc thorac res 2016;8(2):49-55. doi: 10.15171/jcvtr.2016.10. safety of percutaneous aortic valve insertion. a systematic review by hans van brabandt et al., bmc cardiovascular disorders20099:45 doi: 10.1186/1471-2261-9-45 chen c, zhao z-g, liao y-b, peng y, meng q-t, chai h, et al. (2015) impact of renal dysfunction on mid-term outcome after transcatheter aortic valve implantation: a systematic review and meta-analysis. plos one 10(3):e0119817. doi:10.1371/journal.pone.0119817 clinical update:aortic stenosis and coronary artery disease:what do we know? what don’t we know?a comprehensive review of the literature with proposed treatment algorithms by jean-michel paradis et al., european heart journal (2014) 35, 2069–2082 doi:10.1093/eurheartj/ehu247 aortic stenosis and mitral regurgitation as predictors of atrial fibrillation during 11 years of follow-up by veronica widgren et al., bmc cardiovascular disorders201212:92 doi: 10.1186/1471-2261-12-92


Other articles: cornell university college of veterinary medicine aortic/subaortic stenosis pet md heart (aortic) valve narrowing in dogs pet education aortic stenosis: a congenital heart problem merck veerinary manual aortic stenosis


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