aortic-stenosis
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Aortic stenosis

Aortic stenosis

Last Reviewed : 12/24/2020
Aortic stenosis

Aortic stenosis (AS or AoS) is the narrowing of the exit of the left ventricle of the heart, such that problems result. It may occur at the aortic valve as well as above and below this level. It typically gets worse over time. Symptoms often come on gradually with a decreased ability to exercise often occurring first. If heart failure, loss of consciousness, or heart related chest pain occurs due to AS the outcomes are worse. Loss of consciousness typically occurs with standing or exercise. Signs of heart failure include shortness of breath especially when lying down, at night, or with exercise, and swelling of the legs. Thickening of the valve without narrowing is known as aortic sclerosis.

Causes include being born with a bicuspid aortic valve and rheumatic fever. A bicuspid aortic valve affects about one to two percent of the population while rheumatic heart disease mostly occurring in the developing world. A normal valve, however, may also harden over the decades. Risk factors are similar to those of coronary artery disease and include smoking, high blood pressure, high cholesterol, diabetes, and being male. The aortic valve usually has three leaflets and is located between the left ventricle of the heartand the aorta. AS typically results in a heart murmur. Its severity can be divided into mild, moderate, severe, and very severe based on ultrasound of the heart findings.

 

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.

 

Basic information:

https://medlineplus.gov/ency/article/000178.htm medline plus aortic stenosis

http://www.heart.org/heartorg/conditions/more/heartvalveproblemsanddisease/problem-aortic-valve-stenosis_ucm_450437_article.jsp#.v5ybw9kufp0 problem: aortic valve stenosis

http://www.mayoclinic.org/diseases-conditions/aortic-stenosis/basics/definition/con-20026329 mayoclinic anthrax

http://www.webmd.com/heart-disease/tc/aortic-valve-stenosis-overview web md aortic valve stenosis - topic overview

http://www.healthline.com/health/aortic-stenosis health line aortic valve stenosis

https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/aortic-stenosis better health aortic stenosis

http://www.nhs.uk/conditions/aorticvalvereplacement/pages/whyitisnecessary.aspx nhs uk aortic valve replacement - why it's done

http://www.nytimes.com/health/guides/disease/aortic-stenosis/overview.html new york times aortic stenosis

https://www.verywell.com/aortic-stenosis-1745421 very well aortic stenosis

 

Advanced information:

http://patient.info/health/aortic-stenosis-leaflet patient aortic stenosis

http://www.medicinenet.com/aortic_stenosis/article.htm medicine net anthrax

http://emedicine.medscape.com/article/150638-overview medscape anthrax

http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/cardiology/aortic-valve-disease/ cleveland clinic aortic valve disease

http://www.aafp.org/afp/2016/0301/p371.html aortic stenosis: diagnosis and treatment brian h. grimard, md; robert e. safford, md, phd; and elizabeth l. burns, md, mayo medical school, jacksonville, florida am fam physician. 2016 mar 1;93(5):371-378.

https://ghr.nlm.nih.gov/condition/supravalvular-aortic-stenosis genetics home reference supravalvular aortic stenosis

http://www.healio.com/cardiology/learn-the-heart/cardiology-review/aortic-stenosis/introduction-and-etiology healio aortic valve stenosis

http://radiopaedia.org/articles/aortic-valve-stenosis radiopedia aortic valve stenosis

university of pennsylvania school of medicine. "one-third of patients with low flow aortic stenosis do not improve with transcatheter aortic valve replacement, research finds: patients who do not improve with tavr are found to have worse clinical outcomes at one year." sciencedaily. sciencedaily, 15 june 2016. www.sciencedaily.com/releases/2016/06/160615134745.htm .

http://nyulangone.org/conditions/aortic-valve-disease-in-adults/types types of aortic valve disease

 

Research:

http://www.nejm.org/doi/full/10.1056/nejmoa022021#t=article nitroprusside in critically ill patients with left ventricular dysfunction and aortic stenosis by umesh n. khot, m.d n engl j med 2003; 348:1756-1763may 1, 2003doi: 10.1056/nejmoa022021

http://www.aacn.org/wd/cetests/media/c132.pdf aortic stenosis: pathophysiology,diagnosis, and medical management of nonsurgical patients theresa cary, rn, msn, acns-bc, ccrn, chfn judith pearce, rn, bsn, ccrn

http://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-2-9 surgery for severe aortic stenosis with low transvalvular gradient and poor left ventricular function – a single centre experience and review of the literature by andreas borowski et al., journal of cardiothoracic surgery20072:9 doi: 10.1186/1749-8090-2-9

http://jctm.mums.ac.ir/article_6952_acb6808c6eb2e8475353448ced02f417.pdf transcatheter aortic valve replacement: a review article by juan a siordia et al., j cardiothorac med. 2016; 4(2):423-436.

http://www.hindawi.com/journals/crp/2012/145202/ katie l. losenno, robert l. goodman, and michael w. a. chu, “bicuspid aortic valve disease and ascending aortic aneurysms: gaps in knowledge,” cardiology research and practice, vol. 2012, article id 145202, 16 pages, 2012. doi:10.1155/2012/145202

http://cardiovascularultrasound.biomedcentral.com/articles/10.1186/1476-7120-4-27 epidemiology and cardiovascular risk factors of aortic stenosis by pompilio faggiano et al., cardiovascular ultrasound20064:27 doi: 10.1186/1476-7120-4-27

franco a, gerli c, ruggeri l, monaco f. anesthetic management of transcatheter aortic valve implantation. ann card anaesth [serial online] 2012 [cited 2016 jul 29];15:54-63. available from: http://www.annals.in/text.asp?2012/15/1/54/91484

http://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-2-42 hyperdominant left anterior descending artery continuing across left ventricular apex as posterior descending artery coexistent with aortic stenosis by kalyana javangula and pankaj kaul journal of cardiothoracic surgery20072:42 doi: 10.1186/1749-8090-2-42

http://journals.tbzmed.ac.ir/jcvtr/manuscript/jcvtr-8-49.pdf afshar ah, pourafkari l, nader nd. periprocedural considerations of transcatheter aortic valve implantation for anesthesiologists. j cardiovasc thorac res 2016;8(2):49-55. doi: 10.15171/jcvtr.2016.10.

http://bmccardiovascdisord.biomedcentral.com/articles/10.1186/1471-2261-9-45 safety of percutaneous aortic valve insertion. a systematic review by hans van brabandt et al., bmc cardiovascular disorders20099:45 doi: 10.1186/1471-2261-9-45

http://europepmc.org/backend/ptpmcrender.fcgi?accid=pmc4368625&blobtype=pdf chen c, zhao z-g, liao y-b, peng y, meng q-t, chai h, et al. (2015) impact of renal dysfunction on mid-term outcome after transcatheter aortic valve implantation: a systematic review and meta-analysis. plos one 10(3):e0119817. doi:10.1371/journal.pone.0119817

http://eurheartj.oxfordjournals.org/content/ehj/35/31/2069.full.pdf clinical update:aortic stenosis and coronary artery disease:what do we know? what don’t we know?a comprehensive review of the literature with proposed treatment algorithms by jean-michel paradis et al., european heart journal (2014) 35, 2069–2082 doi:10.1093/eurheartj/ehu247

http://bmccardiovascdisord.biomedcentral.com/articles/10.1186/1471-2261-12-92 aortic stenosis and mitral regurgitation as predictors of atrial fibrillation during 11 years of follow-up by veronica widgren et al., bmc cardiovascular disorders201212:92 doi: 10.1186/1471-2261-12-92

 

Other articles:

http://vet.cornell.edu/hospital/services/companion/cardiology/conditions/subaortic-stenosis.cfm cornell university college of veterinary medicine aortic/subaortic stenosis

http://www.petmd.com/dog/conditions/cardiovascular/c_dg_aortic_stenosis pet md heart (aortic) valve narrowing in dogs

http://www.peteducation.com/article.cfm?c=2+2096&aid=838 pet education aortic stenosis: a congenital heart problem

http://www.merckvetmanual.com/mvm/circulatory_system/congenital_and_inherited_anomalies_of_the_cardiovascular_system/aortic_stenosis.htmlthe merck veerinary manual aortic stenosis

 

Related videos:

https://www.youtube.com/watch?v=6qzjswudn3c understanding aortic stenosis with dr. marc gillinov

https://www.youtube.com/watch?v=z9cuxsaiznw aortic stenosis explained clearly

https://www.youtube.com/watch?v=gbk2465ho98 aortic stenosis

https://www.youtube.com/watch?v=gyodhypasis aortic stenosis in seniors explained

https://www.youtube.com/watch?v=3t1n5szxriq aortic stenosis and aortic regurgitation

https://www.youtube.com/watch?v=zglpx9nx_b0 heart sounds - aortic stenosis vs aortic regurgitation

https://www.youtube.com/watch?v=mjg257pyt4i animated aortic stenosis murmur

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