anaphylaxis
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Anaphylaxis

Anaphylaxis

Last Reviewed : 12/24/2020
Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. It typically causes more than one of the following: an itchy rash, throat or tongue swelling, shortness of breath, vomiting, lightheadedness, and low blood pressure. These symptoms typically come on over minutes to hours. Common causes include insect bites and stings, foods, and medications. Other causes include latex exposure and exercise. Additionally, cases may occur without an obvious reason. The mechanism involves the release of mediators from certain types of white blood cells triggered by either immunologic or non-immunologic mechanisms. Diagnosis is based on the presenting symptoms and signs after exposure to a potential allergen. The primary treatment of anaphylaxis is epinephrine injection into a muscle, intravenous fluids, and positioning the person flat. Additional doses of epinephrine may be required. Other measures, such as antihistamines and steroids, are complementary. Carrying an epinephrine auto injector and identification regarding the condition is recommended in people with a history of anaphylaxis.

 

We researched this topic for you and found the following best online resources. They are categorized into basic, advanced, and research level based on the extent of information you need. You will be taken to the respective websites by pressing on the links below.

 

Basic Information:

http://www.mayoclinic.org/diseases-conditions/anaphylaxis/basics/definition/con-20014324 definition

https://www.nlm.nih.gov/medlineplus/ency/article/000844.htm medline plus anaphylaxis

http://acaai.org/allergies/anaphylaxis american college of allergy,asthma and immunology overview

http://www.webmd.com/allergies/guide/anaphylaxis webmd allergies and anaphylaxis

http://www.allergy.org.au/patients/about-allergy/anaphylaxis australasian society of clinical immunology and allergy ascia anaphylaxis

http://www.nhs.uk/conditions/anaphylaxis/pages/introduction.aspx nhs choices anaphylaxis

http://www.msdmanuals.com/home/immune-disorders/allergic-reactions-and-other-hypersensitivity-disorders/anaphylactic-reactions msd manual anaphylactic reactions by peter j. delves, phd(consumer version)

http://www.allergy.org.nz/a-z+allergies/anaphylaxis.html allergy newzealand anaphylaxis

http://www.healthline.com/health/anaphylaxis#overview1 healthline anaphylaxis overview.

https://www.allergyuk.org/severe-allergy-and-anaphylaxis/anaphylaxis allergyuk anaphylaxis and severe allergic reactions

https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/anaphylaxis better health channel anaphylaxis - severe allergic reaction

http://www.dermnetnz.org/reactions/anaphylaxis.html dermnet nz anaphylaxis

https://my.clevelandclinic.org/health/diseases_conditions/hic_anaphylaxis cleveland clinic anaphylaxis

http://www.medicalnewstoday.com/articles/216062.php medicalnewstoday what is anaphylaxis?

http://www.everydayhealth.com/anaphylaxis/ everyday health what is anaphylaxis?by cathy cassata, medically reviewed by robert jasmer, md

http://rarediseases.org/rare-diseases/anaphylaxis/ national organisation for rare disorders. anaphylaxis

http://www.aboutkidshealth.ca/en/healthaz/conditionsanddiseases/allergyandimmunesystemdisorders/pages/anaphylaxis.aspxaboutkidshealth anaphylaxis: how to recognize and respond to a severe allergic reaction

 

Advanced information:

http://www.worldallergy.org/professional/allergic_diseases_center/anaphylaxis/anaphylaxissynopsis.php world allergy organisation. anaphylaxis: synopsis

http://emedicine.medscape.com/article/135065-overview#a2 medscape anaphylaxis author: s shahzad mustafa, md

http://www.uptodate.com/contents/anaphylaxis-symptoms-and-diagnosis-beyond-the-basics uptodate patient information: anaphylaxis symptoms and diagnosis (beyond the basics)

http://patient.info/health/anaphylaxis-leaflet patient info anaphylaxis

http://www.rch.org.au/clinicalguide/guideline_index/anaphylaxis/ the royal childerns hospital melbourne anaphylaxis

https://www.det.nsw.edu.au/media/downloads/what-we-offer/regulation-and-accreditation/early-childhood-education-care/anaphylaxis_guide.pdf nsw governamenteducation and communities anaphylaxis - guidelines for early childhood educationand care services

http://education.qld.gov.au/schools/healthy/anaphylaxis.html queensland government education, anaphylaxis management

http://kidshealth.org/en/parents/anaphylaxis.html kids health from nemours severe allergic reactions(anaphylaxis).

http://pediatrics.aappublications.org/content/111/supplement_3/1601 aap gateway pediatrics june 2003, volume 111 / issue supplement 3 anaphylaxis and emergency treatment by hugh a. sampson.

http://www.racgp.org.au/afp/2012/june/anaphylaxis-recognition-and-management/ australian family physician emergency care june 2012 anaphylaxis - recognition and management by shelley j kirkbright,simon ga brown volume 41, no.6, june 2012 pages 366-370.

http://umm.edu/health/medical/altmed/condition/anaphylaxis university of maryland medical center anaphylaxis

http://www.fpnotebook.com/ent/allergy/anphylxs.htm family practise notebook anaphylaxis

http://www.allerject.ca/en/what-is-anaphylaxis allerject about anaphylaxis

https://www.gov.mb.ca/health/publichealth/cdc/protocol/anaphylactic.pdf protocol in management of suspected anaphylactic shock.

http://lifeinthefastlane.com/ccc/anaphylaxis/ fastlane anaphylaxis overview

http://www.users.globalnet.co.uk/~aair/anaphylaxis.htm asthma and allergy information and research. anaphylaxis -life-threatening allergy.

http://www.chop.edu/clinical-pathway/anaphylaxis-emergent-care-clinical-pathway the childrens hospital of philadelphia ed pathway for evaluation/treatment of children with anaphylaxis

http://www.australianprescriber.com/magazine/34/4/article/1210.pdf australian prescriber. anaphylaxis emergency management for health professionals.

https://www.apls.org.au/sites/default/files/uploadedfiles/algorithms%20-%20anaphylaxis.pdf apls anaphylaxis management

http://www.bpac.org.nz/bpj/2008/december/docs/bpj18_anaphylaxis_pages_10-19.pdf

 

Research:

http://onlinelibrary.wiley.com/doi/10.1111/all.12437/pdf allergy eaaci-european journal of allergy and clinical immunology. muraro a, roberts g, worm m, bilo mb, brockow k, fern andez rivas m, santos af, zolkipli zq, bellou a, beyer k, bindslev-jensen c,cardona v, clark at, demoly p, dubois aej, dunngalvin a, eigenmann p, halken s, harada l, lack g, jutel m, niggemann b, ru?ff f, timmermans f, vlieg–boerstra bj, werfel t, dhami s, panesar s, akdis ca, sheikh a on behalf of the eaaci food allergy and anaphylaxis guidelines group. anaphylaxis: guidelines from the european academy of allergy and clinical immunology. allergy 2014; 69: 1026–1045.

http://www.ijccm.org/article.asp?issn=0972-5229;year=2014;volume=18;issue=12;spage=796;epage=806;aulast=patel

Research article

year : 2014 | volume : 18 | issue : 12 | page : 796-806

drug-induced anaphylactic reactions in indian population: a systematic review by tejas k patel et al doi: 10.4103/0972-5229.146313

http://www.hindawi.com/journals/ja/2012/316296/ journal of allergy
volume 2012 (2012), article id 316296, 7 pages
http://dx.doi.org/10.1155/2012/316296 review article:managing anxiety related to anaphylaxis in childhood: a systematic review by katharina manassis.

http://f1000research.com/articles/4-1492/v1 irani am and akl eg. management and prevention of anaphylaxis [version 1; referees: 2 approved]. f1000research 2015, 4(f1000 faculty rev):1492
(doi: 10.12688/f1000research.7181.1)

http://publications.drdo.gov.in/ojs/index.php/dsj/article/view/2317 defence science journal, 2012, 62(5), pp.307-314, doi:http://dx.doi.org/10.14429/dsj.62.2317 autoinjector device for rapid administration of life saving drugs in emergency (review paper) by r vijayaraghavan

http://aacijournal.biomedcentral.com/articles/10.1186/1710-1492-3-4-134 food-dependent exercise-induced anaphylaxis: a case related to chickpea ingestion and review by chet g. wong and sean r. mace allergy, asthma & clinical immunology20073:134 doi: 10.1186/1710-1492-3-4-134, canadian society of allergy and clinical immunology 2007 published: 15 december 2007

http://www.hindawi.com/journals/jir/2005/829251/abs/ clinical and developmental immunology
volume 12 (2005), issue 4, pages 281-287
http://dx.doi.org/10.1080/17402520500376277 why do people die of anaphylaxis?—a clinical review arvind kumar, suzanne s. teuber, and m. eric gershwin

 

Related topics:

http://vaccine-safety-training.org/anaphylaxis.html vaccine safety basis anaphylaxis

http://www.phac-aspc.gc.ca/publicat/cig-gci/p02-03-eng.php public health agency of canada.vaccine safety early vaccine reactions including anaphylaxis

http://www2.gnb.ca/content/dam/gnb/departments/h-s/pdf/en/cdc/healthprofessionals/anaphylaxis-management_en.pdf new nouveau brunswick canada. protocol for the management of immunization-related anaphylaxis in non-hospital settings

http://www.immune.org.nz/sites/default/files/resources/aefianaphylaxisimac201003v02final.pdf immunization advisory centre anaphylaxis and vaccination .

 

Other articles:

http://www.peteducation.com/article.cfm?c=2+2111&aid=507 pet education.com

anaphylaxis in dogs: severe acute allergic reactions

veterinary & aquatic services department, drs. foster & smith

http://www.2ndchance.info/anaphylaxis.htm preventing anaphylaxis acute allergic shock in dogs, cats and ferrets vaccine reactions.

http://www.petmd.com/dog/conditions/respiratory/c_multi_anaphylaxis petmed anaphylaxis in dogs

 

Other helpful resources(support groups):

http://www.irishanaphylaxis.org/ anaphylaxis ireland

http://www.allergyaware.ca/ allergyaware.ca

http://www.foodallergyawareness.org/ faact

http://www.lifesavingsociety.com/first-aid/anaphylaxis-rescuer.aspx life saving society.

 

Related videos:

http://www.anaphylaxis.org.uk/corporate/corporate-what-is-anaphylaxis/corporate-signs-and-symptoms/ anaphylaxis campaign what is anaphylaxis?

http://www.realfirstaid.co.uk/anaphylaxis/ anaphylactic allergic reaction

https://www.khanacademy.org/science/health-and-medicine/circulatory-system-diseases/shock/v/anaphylactic-shock

https://www.youtube.com/watch?v=gdffid-htba anaphylaxis- pathophysiology

https://www.youtube.com/watch?v=g9d-vfmbt4s animation describing anaphylaxis and the bodies physiologic response , moa, mechanism of action

https://www.youtube.com/watch?v=0wkyln_7pls first aid for anaphylaxis : anaphylactic emergency treatment

 

Presentations/quiz/newspaper articles:

https://www.aaaai.org/conditions-and-treatments/allergies/anaphylaxis/anaphylaxis-quiz.aspx american academy of allergy,asthma and immunology.

http://www.medicinenet.com/allergies_quiz/quiz.htm medicinenet.com

http://www.aafa.org/media/anaphylaxis-in-america-press-release-2015.pdf asthma and allergy foundation of america - new survey reveals deficiencies in care for patients with severe allergic reactions,press release

http://www.nytimes.com/health/guides/disease/anaphylaxis/overview.html the newyork times health guide anaphylaxis

http://www.emedicinehealth.com/allergies_quiz_iq/quiz.htm emedicinehealth allergies quiz: test your medical iq

http://www.lifescript.com/health/centers/anaphylaxis/quizzes/anaphylaxis_quiz.aspx lifescript what’s your anaphylaxis iq?

http://www.cbc.ca/news/health/anaphylaxis-allergies-young-people-deaths-1.3238401 cbc news anaphylaxis often kills teens, youth, experts say.andrea mariano, 18, died sept. 18 after an anaphylactic allergic reaction by aleksandra sagan, cbc news posted: sep 23, 2015 5:00 am et

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