Anal cancer is a cancer (malignant tumor) which arises from the anus, the distal opening of the gastrointestinal tract. It is a distinct entity from the more common colorectal cancer.
Anal cancer is typically an anal squamous cell carcinoma that arises near the squamocolumnar junction, often linked to human papillomavirus (HPV) infection. It may be keratinizing (basaloid) or non-keratinizing (cloacogenic). Other types of anal cancer areadenocarcinoma, lymphoma, sarcoma or melanoma. From data collected 2004-2010, the relative five year survival rate in the United States is 65.5%, though individual rates may vary depending upon the stage of cancer at diagnosis and the response to treatment.
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http://www.em-consulte.com/en/article/212420 sentinel lymph node biopsy in anal cancer: a review by m. mistrangelo gastroentérologie clinique et biologique
volume 33, n° 5 pages 446-450 (mai 2009) doi : 10.1016/j.gcb.2009.01.009