Acute Myeloid Leukemia is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute leukemia affecting adults, and its incidence increases with age. Although AML is a relatively rare disease, accounting for roughly 1.2% of cancer deaths in the United States, its incidence is expected to increase as the population ages,
with an estimated 19,950 new cases and 10,430 deaths anticipated in 2016.
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http://dmm.biologists.org/content/7/8/941. Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer? Carolyn S. Grove, George S. Vassiliou, Disease Models and Mechanisms 2014 7: 941-951; doi: 10.1242/dmm.015974